The startup manufactures biopharmaceuticals with automated systems and consumables designed for laboratory and GMP environments, implementing continuous processing to enhance operational efficiency. Their solutions enable clients to achieve higher productivity, reduced capital expenditures, and minimized facility space requirements.
Funding
$12.8M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
BIFounders
Product
Problem
Traditional biopharmaceutical manufacturing processes using fed-batch methods are inefficient, requiring large capital expenditures, extensive facility space, and resulting in lower productivity. These limitations hinder the ability to meet the growing demand for biotherapeutics while maintaining cost-effectiveness.
Solution
PAK BioSolutions provides comprehensive, automated systems and consumables designed for continuous biopharmaceutical manufacturing in both laboratory and GMP environments. Their PAK systems integrate multiple unit operations, such as diafiltration, filtration, chromatography, inline concentration, and viral inactivation, into a single, continuous process. This approach increases productivity by up to 4x compared to traditional fed-batch processes, reduces capital expenditures by 50% by eliminating stainless steel hold tanks and piping, and minimizes facility footprint by up to 60%. The systems are available in benchtop, pilot, and commercial scales, facilitating seamless process scaling from R&D to GMP manufacturing.
Target Audience
The primary target audience includes biopharmaceutical manufacturers, process development teams, and research facilities seeking to enhance productivity, reduce costs, and minimize facility footprint in biomanufacturing.
Features
- End-to-end continuous purification, integrating multiple unit operations into a single system
- Automated sanitization, equilibration, steady-state operation, and shutdown procedures
- Proprietary disposable flow kits, including mixing vessels, static mixers, instrumentation, and sample ports
- PurSync Automation, allowing users to select any order of unit operations
- Dual-column chromatography for semi-continuous bind and elute processes
- Single-pass tangential flow filtration (SPTFF) for inline concentration
- Integrated diafiltration capabilities for buffer exchange
- Real-time adaptive control system, eliminating the need for a separate SCADA system
- 21 CFR Part 11 compliant automation
- USP Class VI materials