Opera Bioscience utilizes a microbial platform to produce high-purity, soluble recombinant proteins without the complications of inclusion bodies or extensive purification processes. This approach significantly reduces costs and time for researchers by providing affordable, animal-free reagents and materials essential for biomanufacturing.
Funding
$150K raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.

BIFounders
Product
Problem
Recombinant protein production often suffers from low yields, misfolding, and the formation of insoluble inclusion bodies, necessitating complex and costly purification processes. Traditional methods also rely on animal-derived components, raising ethical and safety concerns for biomanufacturing applications.
Solution
Opera Bioscience offers a microbial protein expression platform that secretes high-purity, soluble, and correctly folded recombinant proteins directly from the cell, eliminating the need for extensive purification. This single-step secretion process avoids inclusion bodies, reduces endotoxin contamination, and simplifies downstream processing. The platform enables high yields of proteins, enzymes, and growth factors that are typically difficult to express in microbial systems. By providing affordable, animal-free reagents, Opera Bioscience aims to make biomanufacturing more accessible and sustainable.
Target Audience
The primary customers are researchers and biomanufacturers seeking affordable, high-quality, and animal-free recombinant proteins for various applications.
Features
- Microbial platform for direct secretion of soluble, high-purity recombinant proteins
- Avoidance of inclusion bodies and reduced endotoxin levels compared to traditional methods
- Animal-free production process for ethical and safe biomanufacturing
- High yields of difficult-to-express proteins, enzymes, and growth factors
- Simplified downstream processing with minimal purification requirements