onCyt offers automated laboratory equipment and software for high-resolution microbial monitoring. Their systems enable researchers and manufacturers to gain detailed insights into microbial cultures, improving process control and accelerating research.
Funding
Funding not disclosed
Founders
Product
Problem
Current methods for monitoring microbial cultures in bioprocess development rely on manual sampling and offline testing, which are complex, error-prone, expensive, and delay critical insights. This restricts timely decision-making and process optimization.
Solution
onCyt provides automated laboratory equipment and software for real-time, high-resolution microbial monitoring in bioprocesses. Their online flow cytometry solutions automate sample acquisition, preparation, and analysis, enabling continuous in-process monitoring of key performance indicators (KPIs) such as viable cell count, product titer, and cell phenotype. The system integrates automated sampling, pre-dilution, fluorescent marking, rapid optical detection, and automated data analysis, delivering comprehensive insights into cell parameters and population dynamics. This allows for early detection of process deviations, real-time optimization of feeding strategies, and enhanced overall process control.
Target Audience
The primary customers are researchers and manufacturers in bioprocess development, cell and gene therapy, fermentation, water quality monitoring, and related fields.
Features
- Automated sampling and pre-dilution of microbial cultures
- Fluorescent marking and rapid optical detection for cell analysis
- Online flow cytometry for continuous, automated, high-resolution cell analysis
- Automated data analysis and live view via cyOn software
- OC-300 automation add-on for flexible integration with existing flow cytometers or analyzers
- OC-400 MicroQuant online flow cytometer for gentle sample handling and rapid optical detection
- Automated DAPI staining assay for cell density quantification and community analysis
- Double staining method (DAPI + Alexa 488) for quantifying bacterial cell concentration and active DNA synthesis