Octant Bio develops high-throughput synthetic biology and chemistry technologies to engineer small molecules that modulate complex cellular mechanisms involved in diseases caused by protein misfolding and mistrafficking. Their platform utilizes barcoded multiplexing and AI/ML analytics to generate insights from extensive datasets, enhancing drug discovery efficiency and precision.
Funding
$114.9M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
CCFounders
Product
Problem
Many drug discovery programs focus on binding molecules to a purified "target" protein, which may not effectively address complex cellular mechanisms that drive disease. Diseases caused by protein misfolding and mistrafficking are particularly challenging to address with traditional methods.
Solution
Octant Bio engineers biology and chemistry at massive scales to modulate cellular function, targeting complex mechanisms that drive diseases of protein misfolding and mistrafficking. Their platform utilizes high-throughput synthetic biology to build custom sensors in human cells, modeling how drug candidates affect cellular function when interacting with misfolded proteins. High-throughput chemistry enables exploration of chemical diversity in living cells. Barcoded multiplexing quantifies subtle effect sizes across thousands of experiments, powering direct-to-biology chemistry and generating large AI/ML datasets. AI/ML pipelines and tools process and accelerate the platform, generating insights from millions of data points to advance drug programs.
Target Audience
The primary audience includes pharmaceutical companies and research institutions focused on developing small molecule therapeutics for diseases caused by protein misfolding and mistrafficking.
Features
- High-throughput synthetic biology for building custom sensors in human cells
- High-throughput chemistry for exploring chemical diversity in living cells
- Barcoded multiplexing for massively parallel drug discovery
- Proprietary chemical biology datasets for AI/ML-driven insights
- AI/ML pipelines and tools for processing and accelerating the platform