The startup has developed a three-dimensional humanized adipose tissue model system for in vitro drug discovery, enabling precise disease modeling and cell assays. This technology allows researchers to efficiently identify effective drug compounds for obesity, diabetes, and related metabolic diseases, significantly reducing the time and costs associated with traditional testing methods.
Funding
$4.3M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
TVOLFounders
Product
Problem
Traditional drug discovery methods rely heavily on animal models and animal-derived products like Matrigel, which often fail to accurately mimic human responses and lack representation of diverse patient populations. This can lead to unreliable results, high costs, and delays in identifying effective drug compounds for metabolic diseases.
Solution
Obatala Sciences provides human-derived biomaterials and 3D adipose tissue model systems for in vitro drug discovery, enabling more precise disease modeling and cell assays. Their ObaCell® platform incorporates human diversity, mimicking human biology to improve the accuracy and reliability of preclinical testing. By leveraging human tissue-derived stem cells, hydrogels, and cell culture media, Obatala Sciences offers a fully humanized microphysiological system for drug screening and toxicity testing. This approach accelerates the conversion from animal testing to more effective human-based data, bringing clinically relevant insights to drug developers.
Target Audience
The primary target audience includes researchers in industry and academia, US government entities, contract research organizations, non-profit organizations, and academic research laboratories focused on drug discovery for obesity, diabetes, and related metabolic diseases.
Features
- ObaCell® Fat-on-a-Chip and Obesity-on-a-Chip models engineered to reproduce human biology
- Human-derived hydrogels (ObaGel®) designed to support functional organoid models
- Cell culture media formulated for maintenance and multi-lineage differentiation of human mesenchymal stem cells
- Repository of 200+ cell donors representing a diverse population classified by age, sex, race, BMI, and disease state
- Matrices that support cell proliferation, differentiation, vascularization, and immunogenic responses
- Contract research services including proteomics, lipidomics, metabolomics, multiplex ELISA, and RNA sequencing
- In vitro studies in 2D and 3D systems
- In vivo studies in animal models for skin diseases/injuries, diabetes, cranial defects, and bone repair