The company specializes in a scalable process that transforms single linear chitosan molecules into uniform, bioadherent nanoparticles for applications in medicine, agriculture, and materials science. This technology enhances drug delivery and tissue engineering by providing a reliable method for creating targeted therapeutic agents and diagnostic tools.
Funding
Funding not disclosed
Founders
Product
Problem
Many active pharmaceutical ingredients (APIs) struggle with effective delivery due to poor solubility, rapid systemic distribution, and limited intracellular uptake. Traditional chitosan, while biocompatible, has limitations in achieving uniform particle size and targeted delivery.
Solution
Novochizol provides a technology that transforms linear chitosan molecules into cross-linked, uniformly sized nanospheres, overcoming the limitations of traditional chitosan. These nanospheres can be used as bioadherent carriers for various biologically active substances, including small molecules, peptides, nucleic acids, and proteins. The resulting formulations exhibit strong tissue adherence, sustained local release of APIs without systemic distribution, and enhanced intracellular delivery, even for large proteins. This enables targeted delivery of active ingredients at the site of administration, improving therapeutic efficacy and reducing systemic side effects.
Target Audience
The primary target audience includes pharmaceutical companies, medical device manufacturers, and researchers in tissue engineering, drug delivery, and diagnostics.
Features
- Quantitative transformation of chitosan into uniformly sized nanospheres
- Ability to formulate a wide range of APIs, including small molecules, peptides, nucleic acids, and proteins
- Strong adherence to tissues and materials at the application site
- Injectable, oral, topical, aerosol, and solid matrix formulation options
- Sustained local release of APIs, minimizing systemic distribution
- Enhanced intracellular delivery of macromolecules into various cell types
- GRAS (Generally Recognized As Safe) safety profile inherited from chitosan