NOTA Labs develops a nitric oxide (NO) delivery system that enhances the body's natural NO production to combat viral and bacterial infections, as well as prevent thrombosis during medical procedures. Their technology provides targeted, on-demand NO generation for applications in respiratory infections, open heart surgery, and chronic airway diseases, addressing critical health challenges effectively.
Funding
Funding not disclosed
PTFounders
Product
Problem
Nitric oxide (NO) plays a crucial role in various physiological processes, including immune response, vasodilation, and neurotransmission. Current methods of delivering NO to the body are often inefficient or lack targeted delivery, limiting their effectiveness in treating infections, preventing thrombosis, and managing respiratory conditions. This necessitates innovative approaches to enhance the body's natural NO production and deliver it precisely where needed.
Solution
NOTA Labs is developing two novel NO delivery systems, NOGEN and LANOR, designed to augment the body's natural NO production for treating and preventing life-threatening illnesses. The NOGEN system utilizes an electrochemical process to generate high volumes of NO, suitable for applications such as open-heart surgery (to prevent thrombosis and systemic inflammatory response syndrome) and respiratory infections. The LANOR system employs a compact UV-LED based technology that converts a solid nitric oxide donor molecule using light energy, designed for at-home use for conditions like COPD and catheter-related applications to prevent microbial growth and clotting. These systems aim to provide targeted, on-demand NO generation, addressing critical health challenges effectively.
Target Audience
The primary target audience includes medical professionals in fields such as cardiac surgery, pulmonology, and critical care, as well as patients with respiratory conditions, individuals undergoing open-heart surgery, and those requiring catheterization.
Features
- NOGEN system: Electrochemical NO generation for high-volume delivery.
- LANOR system: UV-LED based technology for converting solid NO donors.
- Targeted NO delivery for respiratory infections, open heart surgery, and chronic airway diseases.
- Prevention of thrombosis and systemic inflammatory response syndrome during extracorporeal circulation.
- Potential applications in treating COPD and preventing catheter-related infections.