NexMR provides key-in-hand solutions for NMR drug discovery pipelines, including platform upgrades, pre-dosed screening chemical kits, and automated analysis software. By enhancing throughput and reducing sample concentration requirements, NexMR enables faster and more cost-effective determination of hit affinities at the atomic scale.
Funding
Funding not disclosed
Founders
Product
Problem
Traditional NMR-based drug discovery pipelines often suffer from low throughput, high sample concentration requirements, and the need for specialized expertise, creating bottlenecks in early-stage hit identification and affinity determination. Existing NMR platforms may lack the sensitivity and automation needed to efficiently screen large chemical libraries and characterize weak binding interactions.
Solution
NexMR offers integrated solutions to enhance the speed, sensitivity, and accessibility of NMR-based drug discovery. The company provides NMR platform upgrades, pre-dosed screening chemical kits, and automated software for data acquisition and analysis. NexMR's technology reduces sample concentration requirements by 10-100 fold and accelerates experimental turnaround by 30-50 fold, enabling faster and more cost-effective determination of hit affinities at the atomic scale, even with benchtop NMR systems. The integrated approach simplifies the NMR workflow, making it accessible to lab technicians without extensive NMR expertise.
Target Audience
The primary target audience includes pharmaceutical companies, biotech firms, and academic research institutions involved in early-stage drug discovery and seeking to improve the efficiency and cost-effectiveness of their NMR pipelines.
Features
- NMR platform upgrades to enhance sensitivity and throughput
- De novo NMR platform design for customized solutions
- Pre-dosed screening chemical kits for efficient library screening
- Affinity determination kits for characterizing binding interactions
- Automated software for screening analysis and hit identification
- Automated software for affinity determination analysis
- Sensitivity-enhanced NMR to accelerate experimental turnaround
- Isotope labeling techniques for determining hit affinities by NMR