NewLimit develops epigenetic reprogramming medicines designed to restore youthful function in aging cells. The company utilizes single-cell genomics, machine learning, and high-throughput assays to identify features of aging and discover rejuvenating interventions. Their initial therapeutic focus targets age-related dysfunction in the liver, immune, and vascular systems to extend human healthspan.
Funding
$72.3M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Aging cells accumulate epigenetic changes that impair their function, contributing to age-related diseases and limiting overall healthspan. The immune system and liver are particularly vulnerable to these age-related declines, impacting their ability to fight off infections and maintain metabolic homeostasis.
Solution
NewLimit is developing epigenetic reprogramming therapeutics designed to restore youthful function to aging cells, with initial focus on the immune system and liver. The company leverages single-cell genomics, machine learning, and high-throughput functional assays to identify and target key epigenetic drivers of aging. By reprogramming the epigenome, NewLimit aims to reverse age-related cellular dysfunction, thereby treating diseases associated with aging and ultimately extending human healthspan. Their approach seeks to rejuvenate cells by resetting their epigenetic state to a younger, more functional profile.
Target Audience
The primary target audience includes individuals at risk of or affected by age-related diseases, as well as researchers and clinicians focused on aging and regenerative medicine.
Features
- Single-cell genomics to map epigenetic changes associated with aging in specific cell types
- Machine learning models to identify key epigenetic targets for reprogramming
- High-throughput functional assays to screen and validate potential therapeutic interventions
- Targeted epigenetic reprogramming of immune cells to enhance immune function in older individuals
- Epigenetic rejuvenation of liver cells to improve metabolic function and reduce age-related liver diseases