Motif Neurotech develops bioelectronic therapeutic Brain Computer Interface (BCI) devices for mental health applications. Their technology measures and regulates specific brain networks to alleviate symptoms of treatment-resistant depression. The implantable system is designed for outpatient procedures, allowing patients to manage their condition from home.
Funding
$21.7M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.



Founders
Product
Problem
Treatment-resistant depression often requires invasive procedures or high doses of medication, presenting significant side effects and limited efficacy for many patients. Current therapeutic options often fail to precisely target and restore healthy brain activity, leaving a substantial unmet need for effective, accessible, and personalized interventions.
Solution
Motif Neurotech is developing a miniature, wireless brain-computer interface (BCI) implant designed to stimulate targeted brain networks and restore healthy brain activity in individuals with treatment-resistant depression. The DOT device is cosmetically invisible, delivered via an outpatient procedure, and designed for at-home use, providing a less invasive alternative to traditional methods. By utilizing innovations in wireless power and data transmission, the implant offers precise tissue stimulation and diagnostic readings, enabling personalized and effective neuromodulation. The device aims to address the biological underpinnings of depression, offering a novel approach to mental health treatment that can be tailored to individual patient needs.
Target Audience
The primary target audience includes individuals with treatment-resistant depression who have not responded adequately to traditional therapies, as well as psychiatrists and medical professionals seeking innovative and effective treatment options for their patients.
Features
- Miniature BCI implant for targeted brain network stimulation
- Wireless power and data transmission for minimally invasive operation
- Outpatient procedure for device implantation
- Designed for convenient at-home use
- Magnetoelectric materials for efficient wireless energy transfer
- Personalized neuromodulation to restore healthy brain activity