Molecular Loop utilizes LoopCap™ technology to integrate target capture and library preparation into a single, scalable workflow for production-scale targeted sequencing applications. This approach addresses the challenges of high-throughput genomic analysis by providing high yield, uniform libraries, and customizable assay design for various research needs.
Funding
$3.3M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional targeted next-generation sequencing (NGS) workflows often involve multiple steps for target capture and library preparation, leading to increased complexity, longer turnaround times, and potential for sample loss. Existing methods may also suffer from biases, resulting in non-uniform library representation and reduced data quality.
Solution
Molecular Loop offers LoopCap™ technology, a method that integrates target capture and library preparation into a streamlined, single-tube workflow for targeted NGS. This approach simplifies the NGS process, reducing hands-on time and minimizing sample handling. LoopCap™ technology utilizes a unique probe structure to enable efficient target enrichment and library construction, resulting in high-yield, uniform libraries suitable for production-scale sequencing applications. The technology's flexibility allows for easy customization of assays, enabling researchers to design targeted sequencing panels tailored to their specific research needs in areas such as infectious disease, inherited disease, and somatic disease analysis.
Target Audience
Molecular Loop's primary customers are researchers and scientists in biopharmaceutical companies, academic institutions, and clinical research organizations who require targeted sequencing for applications such as infectious disease surveillance, inherited disease screening, and somatic mutation detection.
Features
- LoopCap™ technology combines target capture and library preparation in a single-tube reaction.
- Customizable assay design allows for flexible panel creation and content expansion.
- High-yield and uniform libraries minimize bias and improve data quality.
- Validated technology with demonstrated performance in infectious disease, inherited disease, and somatic disease applications.
- Simple and fast protocol reduces hands-on time and turnaround time.
- Expertise in probe design to support the development of custom panels.