MillionMolecules
MillionMolecules is developing a digital PCR system based on centrifugal microfluidics that achieves up to 1,000,000 partitions per sample, combining the absolute quantification of dPCR with the dynamic range, speed, and cost of qPCR. The fully automated platform is designed for high-throughput laboratory use and enables easy migration from existing qPCR workflows. The company is also applying its technology to an EV-based blood test for early prostate cancer diagnosis.
- Biotechnology
- Healthcare Technology
- Medical Devices
- Hardware
Funding
Founders
Founder details are not available yet.
Product
Problem
Current digital PCR (dPCR) technologies offer absolute quantification with high precision, but their limited dynamic range restricts the number of detectable target molecules per sample, forcing users to run multiple dilutions or rely on less sensitive methods. Conventional qPCR systems provide a wide dynamic range but only yield relative quantification, which lacks the precision and reproducibility needed for advanced diagnostic and research applications.
Solution
MillionMolecules is developing a dPCR system based on centrifugal microfluidics that achieves up to 1,000,000 partitions per sample, delivering a dynamic range comparable to qPCR while enabling absolute quantification. The system is designed to combine the high sensitivity and accuracy of dPCR with the speed, price, and workflow convenience of qPCR, allowing users to switch from existing qPCR platforms without major workflow disruptions. The centrifugal-microfluidic filling technology enables a tenfold increase in the number of reactions compared to conventional dPCR systems. The platform is fully automated and optimized for high-throughput scenarios, with short runtimes that support routine laboratory use.
Target Audience
Primary customers are research laboratories, clinical diagnostic providers, and biotechnology companies currently using qPCR or dPCR workflows who require precise, absolute quantification with high throughput and cost efficiency.
Features
- Centrifugal-microfluidic filling technology enabling up to 1,000,000 partitions per sample for high dynamic range
- Absolute quantification of DNA, RNA, and proteins without standard curves
- Dynamic range comparable to qPCR, combining 10x more reactions than conventional dPCR
- Fully automated workflow designed for high-throughput laboratory scenarios
- Short runtimes and qPCR-level pricing to facilitate adoption from existing qPCR setups
- High robustness against inhibitors, supporting accurate results from complex biological samples