Micronbrane Medical develops metagenomic next-generation sequencing (mNGS) technologies that enhance pathogen detection by integrating host depletion and microbial DNA enrichment methods. Their solutions address the limitations of traditional diagnostic techniques, which often fail to accurately identify low-abundance microorganisms and antimicrobial resistance genes, ultimately improving clinical outcomes and research capabilities.
Funding
$4.5M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional metagenomic next-generation sequencing (mNGS) faces challenges due to the overwhelming presence of host, reagent, and environmental contaminants, which obscure microbial signals. This leads to decreased detection sensitivity, increased workflow complexities, and higher costs, hindering accurate and timely microbial data acquisition.
Solution
Micronbrane Medical develops technologies that streamline the mNGS workflow, enhancing pathogen detection through host depletion and microbial DNA enrichment methods. Their product line systematically removes barriers to mNGS adoption, from sample collection to analysis, improving research capabilities and clinical outcomes. By integrating host depletion, the technology improves microbial reads, reduces sequencing depth, and lowers overall costs. The company's solutions deliver results in under 24 hours and accommodate a wide range of sample types and applications.
Target Audience
The primary customers are researchers in microbiome research, clinical microbiologists, and biotechnology companies, as well as those in industrial processes requiring advanced microbial detection and analysis.
Features
- XNA Decontaminating Spray Cleanser: Pre-mixed and stabilized solution that degrades nucleic acids on contact.
- Devin™ Host Depletion Filter: Removes >99% of nucleated host cells.
- Devin™ Microbial DNA Enrichment Kits: Provides 10-1000 fold microbial enrichment with clean, mNGS-grade reagents.
- Unison Ultralow DNA NGS Library Prep Kits: Tn5-based kits with normalizing function.
- PaRTI-Seq RUO/Clinical Analysis: Offers fast cloud-based analysis with automatic cut-offs and on-premise options.
- PureBot and PrepBot Instrumentation: Turnkey mNGS automation solutions.
- Custom collection devices and PathAlert™ rapid antigen tests.