Metrion Biosciences

About Metrion Biosciences

The startup operates a contract research organization that provides preclinical drug discovery screening services, specializing in electrophysiology assays for medicinal chemistry support. Their flexible business models, including fee-for-service and collaborative options, enable clients to access tailored solutions for cardiac safety profiling, neuroscience, and translational assays.

```xml <problem> Drug discovery and development requires robust preclinical screening to identify and optimize drug candidates, particularly for ion channel modulators. Traditional methods can be costly and time-consuming, hindering efficient progress towards clinical development. </problem> <solution> Metrion Biosciences operates as a contract research organization (CRO), providing specialized preclinical drug discovery services focused on ion channel screening, cardiac safety, and neuroscience. They offer tailored solutions, including assay development, high-throughput screening, and detailed characterization of lead compounds. Metrion utilizes electrophysiology and fluorescence-based platforms to deliver high-quality data, supporting medicinal chemistry optimization, cardiac safety profiling, and neuroscience research. Their integrated drug discovery services aim to de-risk ion channel modulators, guiding programs toward clinical development with expertise in translational biology, ADMET, and DMPK. </solution> <features> - Ion channel screening services using automated electrophysiology and fluorescence-based assays - Cardiac safety screening, including GLP hERG testing and CiPA screening - Neuroscience services, including native neuronal ion channel assays and central/peripheral neuronal firing assays - Integrated drug discovery services, combining ion channel biology, medicinal chemistry, and translational biology - Custom assay development and validation for specific targets - High-throughput screening capabilities for early-stage compound screening and lead optimization - Detailed characterization of lead compounds in human cells and native tissues - Translational services, including confirmation of efficacy in stem cell-derived and other phenotypic models - Access to a high-quality small molecule library for hit identification </features> <target_audience> Metrion Biosciences serves pharmaceutical and biotechnology companies, ranging from large pharmaceutical organizations to specialist businesses and academic institutions, seeking preclinical drug discovery services, particularly those focused on ion channels. </target_audience> ```

What does Metrion Biosciences do?

The startup operates a contract research organization that provides preclinical drug discovery screening services, specializing in electrophysiology assays for medicinal chemistry support. Their flexible business models, including fee-for-service and collaborative options, enable clients to access tailored solutions for cardiac safety profiling, neuroscience, and translational assays.

Where is Metrion Biosciences located?

Metrion Biosciences is based in Cambridge, United Kingdom.

When was Metrion Biosciences founded?

Metrion Biosciences was founded in 2015.

How much funding has Metrion Biosciences raised?

Metrion Biosciences has raised 9650000.

Location
Cambridge, United Kingdom
Founded
2015
Funding
9650000
Employees
44 employees
Major Investors
Maven Capital Partners

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Metrion Biosciences

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Executive Summary

The startup operates a contract research organization that provides preclinical drug discovery screening services, specializing in electrophysiology assays for medicinal chemistry support. Their flexible business models, including fee-for-service and collaborative options, enable clients to access tailored solutions for cardiac safety profiling, neuroscience, and translational assays.

metrionbiosciences.com3K+
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Crunchbase
Founded 2015Cambridge, United Kingdom

Funding

$

Estimated Funding

$5M+

Major Investors

Maven Capital Partners

Team (40+)

No team information available.

Company Description

Problem

Drug discovery and development requires robust preclinical screening to identify and optimize drug candidates, particularly for ion channel modulators. Traditional methods can be costly and time-consuming, hindering efficient progress towards clinical development.

Solution

Metrion Biosciences operates as a contract research organization (CRO), providing specialized preclinical drug discovery services focused on ion channel screening, cardiac safety, and neuroscience. They offer tailored solutions, including assay development, high-throughput screening, and detailed characterization of lead compounds. Metrion utilizes electrophysiology and fluorescence-based platforms to deliver high-quality data, supporting medicinal chemistry optimization, cardiac safety profiling, and neuroscience research. Their integrated drug discovery services aim to de-risk ion channel modulators, guiding programs toward clinical development with expertise in translational biology, ADMET, and DMPK.

Features

Ion channel screening services using automated electrophysiology and fluorescence-based assays

Cardiac safety screening, including GLP hERG testing and CiPA screening

Neuroscience services, including native neuronal ion channel assays and central/peripheral neuronal firing assays

Integrated drug discovery services, combining ion channel biology, medicinal chemistry, and translational biology

Custom assay development and validation for specific targets

High-throughput screening capabilities for early-stage compound screening and lead optimization

Detailed characterization of lead compounds in human cells and native tissues

Translational services, including confirmation of efficacy in stem cell-derived and other phenotypic models

Access to a high-quality small molecule library for hit identification

Target Audience

Metrion Biosciences serves pharmaceutical and biotechnology companies, ranging from large pharmaceutical organizations to specialist businesses and academic institutions, seeking preclinical drug discovery services, particularly those focused on ion channels.

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