Marama Labs has developed patented Scatter-Free Absorption (SFA) technology that enhances UV-Vis spectroscopy by eliminating interference from scattered light, enabling accurate quantification of RNA and other biological molecules in nanoparticle formulations. This technology addresses the challenge of light scattering in samples such as liposomes and lipid nanoparticles, facilitating rapid and reliable analysis without prior knowledge of particle size or composition.
Funding
$2.1M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional UV-Vis spectroscopy struggles with accurate quantification of RNA and other biological molecules in nanoparticle formulations due to significant light scattering from the particles themselves. This scattering introduces errors, making it difficult to obtain reliable measurements of drug loading and concentration.
Solution
Marama Labs' Scatter-Free Absorption (SFA) technology enhances UV-Vis spectroscopy by eliminating interference from scattered light, enabling accurate quantification of RNA and other biological molecules in nanoparticle formulations. SFA avoids the need for mathematical corrections or prior knowledge of particle size or composition, providing a direct measurement of the absorption spectrum. This allows for rapid and reliable analysis of samples like liposomes and lipid nanoparticles, which typically scatter light more than they absorb. The CloudSpec instrument utilizes SFA to cut through cloudiness, providing a simple and effective method for UV quantification.
Target Audience
The primary customers are researchers and manufacturers working with nanoparticle formulations, particularly those involved in drug delivery and RNA therapeutics, who require accurate and reliable quantification of biological molecules.
Features
- Patented Scatter-Free Absorption (SFA) technology eliminates light scattering interference.
- Enables accurate quantification of RNA, DNA, and other biological molecules in nanoparticle formulations.
- Measures the absorption spectrum directly without mathematical fitting or corrections.
- Suitable for therapeutic particles <300nm in size, such as liposomes, LNPs, and metal NPs.
- Facilitates non-destructive analysis of samples that scatter light significantly.
- CloudSpec instrument provides rapid and easy quantification and particle characterization.