Mantra Bio develops REVEAL, an exosome engineering platform that utilizes computational biology and lab automation to enhance exosome production and functionality. This technology addresses the challenges of efficient exosome manipulation for therapeutic applications in drug delivery and diagnostics.
Funding
$9M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Exosome-based therapeutics and diagnostics face challenges in efficient production, targeted delivery, and functional enhancement. Traditional methods for exosome engineering are often limited by scalability, reproducibility, and precise control over exosome properties.
Solution
Mantra Bio is developing REVEAL, an exosome engineering platform that leverages computational biology and lab automation to optimize exosome production and functionality. The platform aims to overcome limitations in exosome manipulation by providing a scalable and reproducible method for generating exosomes with enhanced therapeutic potential. REVEAL utilizes computational models to predict optimal engineering strategies, which are then implemented through automated laboratory processes. This approach enables precise control over exosome characteristics, such as targeting ligands and drug encapsulation, to improve delivery and efficacy.
Target Audience
The primary target audience includes pharmaceutical companies, biotechnology firms, and academic researchers involved in developing exosome-based therapeutics and diagnostics.
Features
- Computational modeling for rational design of exosome modifications
- Automated cell culture and exosome isolation for high-throughput production
- Surface engineering to display targeting ligands for specific tissue delivery
- Payload encapsulation for targeted drug delivery
- Quality control assays to ensure exosome purity, size, and functionality
- Scalable manufacturing process for clinical and commercial applications