M20 Genomics offers a single-cell sequencing platform utilizing M20 Seq technology to perform detailed transcriptome analysis across various sample types, including FFPE, frozen, and cultured bacterial samples. This platform enables researchers to investigate cellular heterogeneity and gain insights into gene expression dynamics, which are critical for understanding disease mechanisms and microbial interactions.
Funding
Funding not disclosed
Founders
Product
Problem
Single-cell transcriptome analysis is limited by the challenges of processing diverse sample types, including FFPE, frozen, and cultured bacterial samples, and the need for comprehensive, full-length transcriptome coverage. Existing methods often lack the throughput and sensitivity required for in-depth analysis of complex biological systems.
Solution
M20 Genomics offers the VITA Single-Cell Full-Length Transcriptome Sequencing Platform, powered by M20 Seq technology, to enable comprehensive single-cell transcriptome analysis across a wide range of sample types and species. The VITA platform provides full transcriptome coverage, high sensitivity, and ultra-high throughput, facilitating advanced gene detection and the investigation of cellular heterogeneity. The platform includes the VITAcruizer Single-Cell Partitioning System, VITApilote Library Preparation Kit, and VITAseer Bioinformatics Software, providing an end-to-end solution for single-cell RNA sequencing. M20 Genomics' technology overcomes species barriers, enabling simultaneous RNA profiling across eukaryotes and prokaryotes, including complex microbiomes, and tracks viral and phage activity with single-cell precision.
Target Audience
The primary audience includes researchers in basic research (cancer, neurobiology, immunology), clinical research (oncology, infectious diseases), and drug development, as well as those studying drug resistance, microbe-host interactions, and microbiota function.
Features
- Full transcriptome coverage from the RNA 5' end to 3' end
- Compatible with diverse sample types, including FFPE, frozen tissues, cell suspensions, bacterial suspensions, and microbiome samples
- Applicable to various species, including animals, plants, and microorganisms
- Ultra-high throughput, enabling analysis of up to millions of cells
- High sensitivity for enhanced gene detection at the single-cell level
- Low doublet rate (less than 2% for 10,000 cells)
- Compatible with Illumina and MGI sequencing platforms
- VITAseer Bioinformatics Software streamlines single-cell barcode identification, data quality control, sequence alignment, and gene expression matrix generation
- VITAcruizer Single-Cell Partitioning System with individual valve control, chip identification, and water vapor filtration