Resipher is a real-time, non-invasive oxygen consumption rate (OCR) monitoring system that utilizes patented miniature ultra-sensitive oxygen probes to continuously measure mitochondrial respiration in standard 96-well plates. This technology provides researchers with critical insights into cellular metabolism, enabling long-term tracking of metabolic activity without disturbing the cell culture environment.
Funding
$7M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
ICFounders
Product
Problem
Traditional methods of measuring oxygen consumption rate (OCR) in cell cultures are often invasive and disruptive, hindering long-term monitoring of cellular metabolism. These methods typically require removing the cell culture from its controlled environment, leading to potential alterations in cellular behavior and inaccurate readings.
Solution
Resipher is a real-time, non-invasive system for continuously monitoring oxygen consumption rate (OCR) in standard 96-well plates within a cell culture incubator. The system utilizes patented miniature, ultra-sensitive oxygen probes that magnetically attach to single-use sensing lids, which rest securely on the well plate. These optical sensors measure oxygen concentrations through openings on the underside of the Resipher, characterizing the vertical oxygen gradient that naturally forms above cells as they consume oxygen. Data is streamed in real-time to a cross-platform web application, Lucid Lab, allowing researchers to remotely monitor experiments, generate plots, and analyze detailed O2 analysis. This non-invasive approach enables long-term tracking of metabolic activity without disturbing the cell culture environment, providing valuable insights into cellular health, function, and response to stimuli.
Target Audience
The primary target audience includes cell biologists, metabolic researchers, and drug discovery scientists who require continuous, non-invasive monitoring of cellular respiration in cell culture experiments.
Features
- Non-invasive, continuous OCR monitoring in standard 96-well plates
- Patented miniature, ultra-sensitive oxygen probes for precise measurements
- Real-time data streaming and remote access via Lucid Lab web application
- Comprehensive plots with detailed O2 analysis and reactive controls
- Adaptable tools for flexible plate labeling and well mapping
- Single-use sensing lids to maintain sterility and prevent contamination
- USB-C connection for reliable power and data transfer
- Data export in JSON or CSV formats for use with other software