Loci Orthopaedics
Loci Orthopaedics develops evidence‑based extremity orthopaedic technologies, including the InDx thumb base joint replacement that replicates natural thumb motion with a dual‑axis, six‑degree‑of‑freedom design. The implant is engineered to preserve hand strength, reduce postoperative pain, and provide a joint‑preserving option for patients with severe thumb base arthritis, targeting hand surgeons and orthopaedic specialists.
- Biotechnology
- Healthcare Technology
- Medical Devices
Funding
Raised to date
$14MRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Thumb base arthritis affects up to 10% of the population, with severe symptoms in 5% and a higher prevalence among women over 55. Existing surgical options often result in reduced hand strength or persistent pain, limiting patients’ ability to perform everyday tasks.
Solution
Loci Orthopaedics has developed the InDx implant, a thumb base joint replacement that replicates the natural complex motions of the thumb. The device provides two independent points of rotation, enabling movement in at least six degrees of freedom to fully accommodate the thumb’s range of motion. Designed in collaboration with leading hand surgeons, the implant aims to preserve hand strength while alleviating pain. By offering a patient‑sensitive alternative to traditional surgery, the InDx implant seeks to improve functional outcomes for individuals with severe thumb base arthritis.
Target Audience
Primary customers are hand surgeons and orthopedic specialists treating severe thumb base arthritis, as well as patients seeking a joint‑preserving surgical option.
Features
- Dual‑axis rotation mechanism allowing concurrent, independent movement of the thumb joint
- Six degrees of freedom design to mimic natural thumb kinematics
- Engineered to maintain hand strength and reduce postoperative pain
- Developed with input from world‑leading hand surgeons to meet clinical requirements
- Implant and OsteoAnchor surface architecture optimized for secure fixation and joint stability