Lightcast provides Envisia, a high‑throughput platform that isolates thousands of single cells and directly measures functional behaviours such as biomolecule secretion, cell‑cell communication, and susceptibility to targeted killing. The system combines microfluidic isolation, sensitive detection, and an integrated analytics suite to generate quantitative functional profiles that support antibody discovery, cellular therapy development, and other translational research applications.
Funding
$113.9M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Current single‑cell analysis techniques often focus on static genomic or transcriptomic snapshots and lack the ability to directly measure functional behaviours such as biomolecule secretion, cell‑cell communication, or targeted cell killing at scale. This limits researchers’ capacity to identify functional heterogeneity, isolate optimal producer cells, and develop precise therapeutics.
Solution
Lightcast offers Envisia, a next‑generation platform that enables high‑throughput, functional interrogation of individual cells. The system combines microfluidic isolation with sensitive detection modalities to quantify secreted antibodies, cytokines, and other signalling molecules from single cells. It also captures real‑time cell‑cell interaction events and assesses cell‑specific susceptibility to targeted killing agents. Data are processed through an integrated analytics suite that visualizes functional heterogeneity and supports downstream selection of optimal cell populations for antibody discovery, cellular therapies, and other translational applications. By providing a flexible, scalable solution, Envisia accelerates the translation of functional insights into therapeutic candidates.
Target Audience
Primary customers are academic and industry researchers in biotechnology, pharmaceutical, and cell‑therapy programs who require functional single‑cell data for antibody discovery, T‑cell engineering, cytokine profiling, and related applications.
Features
- Microfluidic workflow that isolates and assays thousands of individual cells in parallel
- Real‑time measurement of biomolecule secretion (e.g., antibodies, cytokines) with single‑cell resolution
- Integrated assays for monitoring direct cell‑cell interactions and communication dynamics
- Targeted cell‑killing modules that evaluate susceptibility of individual cells to therapeutic agents
- Automated data analysis pipeline delivering quantitative functional profiles and visualizations
- Compatibility with downstream workflows for cell sorting, cloning, and therapeutic development