Karnateq provides RNA sequencing library preparation kits that simplify the process and reduce bias. Their OTTR technology and engineered reverse transcriptases enable researchers to generate high-quality libraries from minimal RNA input, improving sequencing results.
Funding
Funding not disclosed
Founders
Product
Problem
Traditional RNA sequencing library preparation methods often suffer from low yields and introduce biases, particularly when working with limited RNA input. These limitations can compromise the accuracy and sensitivity of downstream sequencing results, hindering genomics research.
Solution
Karnateq offers RNA sequencing library preparation kits that simplify the process and minimize bias, enabling researchers to generate high-quality libraries even from minimal RNA input. Their core technology, Ordered Two-Template Relay (OTTR), utilizes engineered eukaryotic reverse transcriptases in a single-tube workflow. This approach connects 5' and 3' adaptor handles to the RNA or DNA ends during cDNA synthesis, facilitating efficient end-to-end sequence capture. The kits provide a streamlined solution for end-to-end RNA sequence capture, improving the overall efficiency and reliability of RNA sequencing workflows.
Target Audience
The primary customers are researchers and scientists in genomics, transcriptomics, and related fields who require robust and reliable RNA sequencing library preparation methods.
Features
- OTTR technology for efficient end-to-end sequence capture
- Engineered eukaryotic reverse transcriptases for improved performance
- Single-tube workflow simplifies library preparation
- Compatible with minimal RNA input
- Reduces bias in NGS library preparation
- Suitable for processed RNA or DNA
- Adaptable to various applications, including ribosome profiling and ncRNA sequencing