JUMPCODE offers CRISPR-mediated rRNA depletion kits, including DepleteX™ and CRISPRclean®, that enhance next-generation sequencing (NGS) workflows by removing uninformative nucleic acids. This technology improves sensitivity and data quality across various genomic applications, including single-cell analysis and microbiome characterization.
Funding
$44.2M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
In next-generation sequencing (NGS), a significant portion of sequenced molecules are often uninformative, leading to reduced sensitivity and inefficient data acquisition. The presence of undesired nucleic acid fragments, such as ribosomal RNA (rRNA), can obscure the detection of relevant genomic information in various applications.
Solution
JUMPCODE provides CRISPR-mediated rRNA depletion kits, including DepleteX™ and CRISPRclean®, designed to enhance NGS workflows by removing these uninformative nucleic acids. This targeted depletion improves the proportion of usable data, boosting sensitivity and data quality across a range of genomic applications. The kits offer both pre-designed and custom depletion panels to remove specific undesired fragments, enabling researchers to focus on the most relevant genomic information. By reducing common noise, JUMPCODE's technology enhances discovery in areas such as single-cell analysis, microbiome characterization, infectious disease detection, and whole transcriptome profiling.
Target Audience
The primary audience includes researchers and scientists in genomics, molecular biology, and related fields who utilize next-generation sequencing for applications such as single-cell analysis, microbiome characterization, infectious disease research, and whole transcriptome profiling.
Features
- CRISPR-mediated depletion of ribosomal RNA (rRNA) and other undesired nucleic acid fragments
- DepleteX™ kit for broad depletion of ribosomal, mitochondrial, and non-variable genes in single-cell analysis
- CRISPRclean® kit for unbiased human DNA and RNA depletion in metagenomics applications
- Targeted depletion of ribosomal and globin RNA, or the top 70% of human mRNA, for whole transcriptome profiling
- Custom depletion panels available for targeting specific sequences in any genomic application, from one to over a million targets
- Plant and animal-specific depletion options for improved GBS and metagenomics in agrigenomics