Ionpath offers a high‑plex spatial biology platform that performs automated multiplexed immunofluorescence staining and sub‑micron optical scanning to generate quantitative protein maps of up to 40 markers on a single tissue section. Integrated de‑convolution, AI‑driven cell segmentation, and cloud‑based data management deliver per‑cell expression matrices and secure API access for downstream bioinformatics. The end‑to‑end workflow reduces sample usage and turnaround time for immunology and oncology research in academic and pharmaceutical labs.
Funding
Funding not disclosed
Founders
Product
Problem
Researchers in immunology and oncology often lack tools that can simultaneously profile dozens of protein markers while preserving spatial context within tissue samples. Conventional assays are limited to a few markers per slide, requiring multiple sections and extensive manual processing, which hampers comprehensive cellular microenvironment analysis.
Solution
Ionpath provides a high‑plex spatial biology platform that enables quantitative, multiplexed imaging of tissue sections in a single workflow. The system combines automated reagent delivery, high‑resolution microscopy, and proprietary image‑analysis algorithms to generate multiplexed protein maps at subcellular resolution. By consolidating multiple markers onto one slide, the platform reduces sample consumption and experimental turnaround time. Processed data are exported in standardized formats for downstream statistical or bioinformatic pipelines, allowing researchers to correlate spatial protein expression with functional phenotypes. The end‑to‑end solution supports both discovery‑phase studies and translational projects that require detailed cellular context.
Target Audience
Primary customers are academic immunology and oncology laboratories, as well as pharmaceutical R&D groups that require high‑dimensional spatial profiling of tissue specimens.
Features
- Automated multiplexed immunofluorescence staining with up to 40 antibody channels per tissue section
- High‑resolution, wide‑field optical scanner delivering sub‑micron pixel size and precise focus control
- Proprietary de‑convolution and spectral unmixing software that resolves overlapping fluorophores with <5 % cross‑talk
- AI‑enhanced cell segmentation and phenotyping pipelines that output per‑cell protein expression matrices
- Cloud‑based data repository with secure, HIPAA‑compliant storage and API access for integration with LIMS or bioinformatics tools
- Customizable antibody panel design tools and validation workflow to accelerate assay development
- Real‑time quality‑control dashboards that monitor staining uniformity, signal‑to‑noise ratio, and instrument performance