Funding
Funding not disclosed
Founders
Product
Problem
Current methods for detecting steroid hormone bioactivity often rely on targeted chemical analysis, which can miss novel designer steroids, hormone mimics from environmental sources, and the combined effects of multiple compounds. These methods may also be time-consuming, costly, and require specialized equipment.
Solution
InsituGen provides cell-free bioassays that offer a rapid, cost-effective, and non-targeted approach to detecting androgen and estrogen bioactivity in various samples. The bioassays replicate natural biological signaling pathways of hormone receptors, enabling the detection of any compound that interacts with these receptors, regardless of its chemical structure. This technology allows for comprehensive screening of samples for total hormone bioactivity, including known and unknown compounds, making it suitable for applications such as anti-doping, supplement testing, animal wellness, and environmental monitoring. InsituGen offers both testing services and ready-to-use kits, including the firstFlagX Androgen bioactivity test kit, to meet diverse customer needs.
Target Audience
InsituGen serves analytical laboratories, sports anti-doping organizations, supplement manufacturers, veterinary professionals, environmental monitoring agencies, and clinical researchers seeking accurate and comprehensive hormone bioactivity testing.
Features
- Cell-free bioassays that mimic natural steroid hormone signaling pathways
- Non-targeted detection of total androgen or estrogen bioactivity, regardless of molecular structure
- Rapid results in under 2 hours using standard laboratory equipment
- Cost-effective screening for individual samples or high-throughput analysis
- Adaptable to various sample types, including plasma, supplements, and environmental samples
- firstFlagX kit available in a 96-well format with fluorescence output for easy reading
- NeuterNow service for veterinarians to assess hormonal maturity in dogs prior to neutering