Inside Therapeutics provides specialized equipment and services for nanoparticle and RNA‑LNP formulation, including the TAMARA microfluidic system for scalable drug development. It offers custom LNP kits, end‑to‑end CRO formulation services, and hands‑on training to accelerate research from proof‑of‑concept to manufacturing. The company also supplies resources such as application notes, calculators, and reviews to support nanomedicine development.
Funding
Funding not disclosed
Founders
Product
Problem
Traditional nanoparticle manufacturing methods often suffer from material waste, scalability issues, and limited control over nanoparticle characteristics, hindering efficient drug development. Transitioning from micro-scale screening to large-scale production can be challenging, requiring significant optimization and adjustments.
Solution
InsideTX offers the TAMARA nanoparticle formulation system, a microfluidic platform designed to streamline the synthesis of lipidic and polymeric nanoparticles for RNA-LNP therapeutics. This system facilitates seamless transitions from micro-scale screening to large-scale production, addressing the challenges of material waste and scalability. The platform provides precise control over nanoparticle characteristics, such as size, polydispersity index (PDI), and encapsulation efficiency (EE), throughout the drug development process. TAMARA enables researchers to work with small volumes, minimizing reagent waste and maximizing yield. The system's reusable chips and integrated cleaning protocol further contribute to cost-effectiveness and ease of use.
Target Audience
The primary target audience includes researchers and pharmaceutical companies involved in RNA-LNP therapeutics development, particularly those focused on optimizing nanoparticle characteristics and scaling up production.
Features
- Microfluidic-based nanoparticle formulation system for lipidic and polymeric nanoparticles
- Seamless scalability from discovery to in vivo testing, handling volumes from 200 µL to 30 mL
- Optimized fluidic design minimizing reagent waste, enabling 100% material use
- Precise control over nanoparticle size (50-200 nm), PDI (<0.2), and EE% (>95%)
- Reusable microfluidic chips with integrated cleaning protocol
- Quick and user-friendly operation, with formulation in under 10 seconds