Infinity Bio provides high-throughput antibody reactome profiling services using its proprietary MIPSA technology. This service decodes antibody binding interactions against comprehensive antigen libraries for various hosts and isotypes. The company supports research across infectious diseases, autoimmunity, vaccine development, and precision medicine by delivering detailed immune response data.
Funding
$4.5M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Understanding the full scope of antibody responses to various antigens is challenging due to limitations in existing technologies regarding library content, throughput, accuracy, and cost-effectiveness. Conventional methods often fail to comprehensively analyze the antibody reactome, hindering advancements in immunology research and personalized medicine.
Solution
Infinity Bio offers comprehensive antibody reactome profiling services using its proprietary Molecular Indexing of Proteins by Self-Assembly (MIPSA) technology. MIPSA employs self-assembly to create a library of in-solution DNA-barcoded antigens. The antibodies in the specimen bind to their target antigens, and the binding is then analyzed via DNA sequencing to determine the presence and levels of each antigen-reactivity. This approach enables researchers to gain detailed insights into immune responses against viruses, allergens, and human proteins, facilitating the discovery of disease mechanisms and the development of improved diagnostics, treatments, and vaccines. The VeraCode system ensures data accuracy by associating DNA barcodes with unmutated versions of the antigen library members.
Target Audience
The primary audience includes researchers, clinicians, and pharmaceutical companies involved in immunology research, vaccine development, autoimmune disease research, allergy research, cancer immunotherapy, and precision medicine.
Features
- Comprehensive antigen library coverage, allowing for the most complete analysis of antibody reactivities
- Ability to combine multiple antigen libraries for optimized coverage and cost-efficiency
- Capacity to create both peptide and full-length protein antigens, providing different levels of information and resolution
- Custom antigen library development, enabling the creation of bespoke libraries from any protein sequence
- VeraCode system, ensuring data accuracy by associating DNA barcodes with unmutated versions of the antigen library members
- Bioinformatics and data analysis services, providing standard reporting and fee-for-service statistical analyses
- Services include VirSIGHT™ for human viruses, AllerSIGHT™ for allergens, HuSIGHT™ for human proteins, and MuSIGHT™ for mouse proteins