Health Technology Innovations provides cryo-electron microscopy (cryo-EM) services and software that automate image processing through its CryoDiscovery™ platform, enhancing the accuracy and efficiency of single particle analysis. This technology accelerates structure-based drug discovery by delivering fast and scalable solutions for 3-D structure modeling in pharmaceutical research.
Funding
$1M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Determining high-resolution 3D structures of biomolecules using cryo-electron microscopy (cryo-EM) is computationally intensive and time-consuming, particularly the steps of particle picking, 2D classification, and 3D classification within single particle analysis workflows. Manual processing introduces user bias and fatigue, potentially impacting the accuracy and reproducibility of results.
Solution
Health Technology Innovations (HTI) offers both cryo-EM services and the CryoDiscovery™ platform, an AI-powered software solution that automates image processing for single particle analysis. HTI partners with a network of image acquisition sites to provide fast, affordable, and scalable access to cryo-EM resources, from protein purification to structure determination. The CryoDiscovery™ platform employs machine learning to automate 2D and 3D class selection, integrating seamlessly with popular image processing software packages. By automating these critical steps, HTI accelerates the structure determination process, reduces user bias, and enhances the accuracy of 3D models.
Target Audience
HTI serves pharmaceutical and biotechnology companies engaged in structure-based drug discovery, as well as research institutions and scientists utilizing cryo-EM for structural biology research.
Features
- AI/ML-based automation of 2D and 3D class selection in cryo-EM image processing
- Seamless integration with popular cryo-EM software packages (open source and commercial)
- Custom protein production and analysis services
- Cryo-EM sample optimization and qualitative sample checks
- Real-time AI/ML grid processing and optimized data collection
- 3D atomic structure determination
- Training and project consultation services
- Access to high-end cryo-EM scopes (Krios, Glacios) and screening scopes (Spirit, Morgagni)