This startup develops a scientific platform that uses optics, image processing, and microfluidics to analyze particles in research processes. Their biopharmaceutical quality control tools provide researchers with insights into the stability and quality of biological drugs.
Funding
$6M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Biopharmaceutical research and development requires accurate and efficient particle analysis to ensure drug stability, efficacy, and safety. Traditional particle analysis methods often require large sample volumes and are limited in their ability to identify and characterize subvisible particles, leading to potential delays and increased costs in drug development.
Solution
Halo Labs provides a particle analysis platform that utilizes optics, image processing, and microfluidics to enable researchers to analyze particles with microliter volumes at high throughput. The Aura family of particle analyzers leverages Backgrounded Membrane Imaging (BMI) and Fluorescence Membrane Microscopy (FMM) technologies to provide comprehensive particle analysis, including particle counting, sizing, morphology, and identification. This allows for earlier detection of potential liabilities, better decision-making during drug development, and support for manufacturing quality control in compliance with USP 788.
Target Audience
The primary target audience includes biopharmaceutical researchers and manufacturers involved in protein and antibody therapeutics, gene therapy, and cell therapy development, as well as quality control personnel requiring USP 788-compliant measurements.
Features
- Backgrounded Membrane Imaging (BMI) for visualizing all particles in a sample, including transparent subvisible particles
- Fluorescence Membrane Microscopy (FMM) for identifying and categorizing particles using extrinsic fluorescent dyes
- Side Illumination Membrane Imaging (SIMI) for characterizing extrinsic and inorganic particles
- High-throughput analysis using 96-well membrane plates, enabling analysis of one sample per minute
- Low sample volume requirements (as little as 5 µL)
- Particle Vue software for image capture and analysis, providing particle size distribution, count, and morphology data
- USP 788 compendial method for particle measurements
- Ability to differentiate and enumerate cells versus Dynabeads