Functional Fluidics provides standardized clinical blood function assays that measure red blood cell health, focusing on specific biomarkers to evaluate individual patient responses, particularly in sickle cell disease. Their proprietary assays, including flow adhesion and mechanical fragility tests, enable healthcare providers and researchers to obtain objective data for improved patient care and drug development.
Funding
Funding not disclosed
Founders
Product
Problem
Current methods for assessing red blood cell (RBC) health often lack the sensitivity to detect subtle functional changes, particularly in diseases like sickle cell disease where RBC dysfunction plays a critical role. This limitation hinders the ability to objectively monitor disease progression, evaluate treatment efficacy, and develop targeted therapies.
Solution
Functional Fluidics offers a suite of standardized clinical blood function assays designed to provide a comprehensive assessment of RBC health. Their CLIA-certified lab employs proprietary assays, including flow adhesion, mechanical fragility, dynamic sickling, and oxygen/osmotic gradient scanning, to quantify key RBC functional parameters. These assays provide objective, validated biomarkers that enable healthcare providers and researchers to gain deeper insights into individual patient responses and RBC behavior under various conditions. By measuring RBC adhesion properties, resistance to mechanical stress, and sickling dynamics, Functional Fluidics delivers actionable data to improve patient care and accelerate drug development in the field of red blood cell disorders. The assays are available nationally to clinical providers, pharmaceutical companies, academic institutions, and biotech partners.
Target Audience
The primary target audience includes clinical providers specializing in hematology, pharmaceutical companies developing RBC-targeted therapies, academic researchers studying red blood cell disorders, and biotech companies seeking advanced diagnostic tools.
Features
- Flow Adhesion Assay: Quantifies the adhesion of red blood cells to the endothelium under controlled flow conditions, mimicking the physiological environment.
- Mechanical Fragility Assay: Measures the susceptibility of red blood cells to mechanical stress, providing insights into membrane stability and overall RBC health.
- Dynamic Sickling Assay: Assesses the rate and extent of red blood cell sickling under deoxygenated conditions, crucial for understanding vaso-occlusive events in sickle cell disease.
- Oxygenscan: Measures the oxygen dissociation curve of red blood cells.
- Osmoscan: Assesses red blood cell response to osmotic stress.
- CLIA-certified laboratory ensures high-quality, reproducible results.
- Contract research services available for customized assay development and validation.