Form Bio

About Form Bio

Form Bio provides a computational platform that utilizes AI models to optimize AAV gene therapy vector design, significantly reducing development time and costs. The platform enhances drug candidate design, test manufacturing, and IND enabling studies by delivering precise assessments of genomic identity, immunogenicity, and manufacturability.

```xml <problem> Developing AAV gene therapies is a time-consuming and expensive process. Optimizing vector design, ensuring manufacturability, and conducting necessary IND-enabling studies present significant challenges. </problem> <solution> Form Bio offers a computational platform that leverages AI models to accelerate and optimize AAV gene therapy development. The platform facilitates rational vector design through _in silico_ assessments of genomic identity, immunogenicity, and manufacturability, enabling exploration of multiple vector designs. By providing detailed analysis of drug substance characterization, multi-candidate comparison, and immunotoxicity analysis, Form Bio helps ensure the production of efficacious and safe drugs with high yield. The platform also streamlines IND-enabling studies, providing critical toxicity and safety data necessary for submission. </solution> <features> - AI-powered candidate optimization using large language models and deep learning to analyze billions of therapeutic construct versions. - _In silico_ tools for assessing vector genomic identity, immunogenicity, and manufacturability. - Drug substance characterization to analyze the manufactured drug product, including the proportion of full AAV viral genomes. - Multi-candidate comparison to evaluate the safety, yield, and expression of multiple AAV constructs. - Immunotoxicity analysis to assess potential risks associated with CpG islands and other viral genomic patterns. - FORMsightAI for elevating construct manufacturability. </features> <target_audience> The primary target audience includes researchers and companies involved in AAV gene therapy development, specifically those focused on drug candidate design, test manufacturing, and IND-enabling studies. </target_audience> ```

What does Form Bio do?

Form Bio provides a computational platform that utilizes AI models to optimize AAV gene therapy vector design, significantly reducing development time and costs. The platform enhances drug candidate design, test manufacturing, and IND enabling studies by delivering precise assessments of genomic identity, immunogenicity, and manufacturability.

Where is Form Bio located?

Form Bio is based in San Francisco, United States.

When was Form Bio founded?

Form Bio was founded in 2022.

How much funding has Form Bio raised?

Form Bio has raised 64000000.

Location
San Francisco, United States
Founded
2022
Funding
64000000
Employees
42 employees
Major Investors
Jazz Venture Partners
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Form Bio

Score: 100/100
AI-Generated Company Overview (experimental) – could contain errors

Executive Summary

Form Bio provides a computational platform that utilizes AI models to optimize AAV gene therapy vector design, significantly reducing development time and costs. The platform enhances drug candidate design, test manufacturing, and IND enabling studies by delivering precise assessments of genomic identity, immunogenicity, and manufacturability.

formbio.com3K+
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Crunchbase
Founded 2022San Francisco, United States

Funding

$

Estimated Funding

$64M+

Major Investors

Jazz Venture Partners

Team (40+)

Ben Lamm

Ben Lamm

Company Description

Problem

Developing AAV gene therapies is a time-consuming and expensive process. Optimizing vector design, ensuring manufacturability, and conducting necessary IND-enabling studies present significant challenges.

Solution

Form Bio offers a computational platform that leverages AI models to accelerate and optimize AAV gene therapy development. The platform facilitates rational vector design through _in silico_ assessments of genomic identity, immunogenicity, and manufacturability, enabling exploration of multiple vector designs. By providing detailed analysis of drug substance characterization, multi-candidate comparison, and immunotoxicity analysis, Form Bio helps ensure the production of efficacious and safe drugs with high yield. The platform also streamlines IND-enabling studies, providing critical toxicity and safety data necessary for submission.

Features

AI-powered candidate optimization using large language models and deep learning to analyze billions of therapeutic construct versions.

_In silico_ tools for assessing vector genomic identity, immunogenicity, and manufacturability.

Drug substance characterization to analyze the manufactured drug product, including the proportion of full AAV viral genomes.

Multi-candidate comparison to evaluate the safety, yield, and expression of multiple AAV constructs.

Immunotoxicity analysis to assess potential risks associated with CpG islands and other viral genomic patterns.

FORMsightAI for elevating construct manufacturability.

Target Audience

The primary target audience includes researchers and companies involved in AAV gene therapy development, specifically those focused on drug candidate design, test manufacturing, and IND-enabling studies.