Foli Bio develops a non-invasive transcriptome platform utilizing proprietary Foli-seq™ technology to profile host RNA from stool samples. This platform generates high-dimensional transcriptomic data providing molecular insights into mucosal biology, immune activation, and barrier integrity. The resulting data supports precision medicine applications including biomarker identification, patient stratification, and therapeutic response prediction for drug development.
Funding
Funding not disclosed
Founders
Product
Problem
Current methods for assessing gut health often rely on non-specific markers, invasive procedures like endoscopies, or infrequent doctor's visits, making it difficult to track daily changes and obtain a comprehensive view of the gastrointestinal tract. Analyzing the ongoing signaling within the gut requires more accessible and high-resolution techniques.
Solution
Foli Bio offers a next-generation platform for non-invasive omics analysis, unlocking the temporal RNA code from the human body using exfoliated material such as stool, urine, and skin. Their proprietary technology analyzes trace amounts of human RNA in these materials to generate a holistic picture of an individual's health. By analyzing RNA in stool specimens, Foli Bio provides insights into the body's dynamics in disease states and upon treatment, offering a global view of signaling throughout the entire gastrointestinal tract. This approach enables analyses comparable in scale and precision to endoscope and biopsy-based transcriptomics studies but at an ultra-high temporal resolution.
Target Audience
Foli Bio partners with fundamental researchers, translational scientists, and clinicians in both academia and the pharmaceutical industry interested in understanding cellular signals within the gut and how those are altered in settings such as disease or therapeutic intervention.
Features
- Comprehensive analysis of human RNA in stool specimens.
- Non-invasive assessment of gut health using exfoliated bodily material.
- Proprietary technology to unlock the temporal RNA code.
- High-resolution insights into the body's dynamics in disease states and upon treatment.
- Analysis comparable to endoscope and biopsy-based transcriptomics studies.
- Ability to analyze samples stored in various settings and time periods.