FIRE1 is developing novel therapeutic devices aimed at enhancing patient outcomes through targeted delivery mechanisms. The startup addresses the need for more effective treatment options in the medical device sector, focusing on improving therapeutic efficacy and patient compliance.
Funding
$120M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
EMFounders
Product
Problem
Heart failure patients often experience a diminished quality of life due to the need for frequent hospital visits and the challenges of managing fluid volume, a critical aspect of their condition. Current methods for monitoring fluid accumulation may not be sensitive enough to detect subtle changes in intravascular volume. This can lead to delayed intervention and potentially adverse outcomes for patients.
Solution
FIRE1 is developing NORM, a novel system for heart failure management that provides direct measurement of fluid volume in the inferior vena cava (IVC). The system comprises a sensor implanted in the IVC, a wearable belt, and a patient-facing mobile app, along with a clinician portal. The sensor measures the cross-sectional area of the IVC, which expands and contracts with the respiratory cycle, reflecting changes in fluid volume. The belt activates the sensor, transmitting data to the cloud, where algorithms process the information and generate insights accessible through the patient and clinician apps. This allows for continuous monitoring of the patient's condition and facilitates timely intervention by the care team, with the goal of reducing hospital visits and improving patient outcomes.
Target Audience
The primary target audience includes heart failure patients seeking improved self-management tools and reduced hospital visits, as well as clinicians and cardiologists involved in heart failure research and treatment.
Features
- Implantable sensor placed in the IVC to directly measure fluid volume
- Non-invasive wearable belt that activates the sensor and transmits data wirelessly
- Patient mobile app for tracking status and receiving guidance from the care team
- Clinician portal for remote monitoring and assessment of patient condition
- Algorithms that process sensor data to generate insights on IVC dynamics
- Early detection of fluid accumulation through sensitive measurement of IVC cross-sectional area
- Facilitates physician-directed patient self-management regimes