Fesarius Therapeutics is developing the DermiSphere™, a micropatterned hydrogel wound dressing that incorporates collagen microspheres to enhance cell invasion and vascularization for full-thickness skin loss treatment. This technology addresses the limitations of traditional wound care by promoting rapid tissue regeneration and improving patient outcomes in a single surgical step.
Funding
$8.5M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Current treatments for full-thickness skin loss often require multiple procedures and may not fully restore the original skin structure and function. Traditional wound care methods can be slow, leading to increased risk of infection and prolonged healing times. Existing solutions may lack the necessary microenvironment to promote optimal cell invasion and vascularization, hindering complete tissue regeneration.
Solution
Fesarius Therapeutics is developing DermiSphere™, a micropatterned hydrogel wound dressing designed to address the challenges of full-thickness skin loss treatment. This innovative dressing incorporates collagen microspheres within a self-assembling hydrogel scaffold, creating an optimized environment for rapid cell invasion and vascularization. DermiSphere™ aims to promote natural tissue growth and healing, potentially achieving complete dermal and epidermal layer reconstitution in a single surgical step. The unique microarchitecture of the collagen spheres is precisely programmed to provide the ideal structure, density, and spacing for healthy tissue cell migration, leading to the formation of a robust and functional neodermis.
Target Audience
The primary target audience includes surgeons and healthcare providers specializing in wound care and reconstructive surgery, seeking advanced solutions for treating full-thickness skin loss.
Features
- Micropatterned hydrogel scaffold with embedded collagen microspheres
- Unique microarchitecture promotes rapid cell invasion and vascularization
- Designed to maintain idealized conditions in the wound bed
- Intended for single-step surgical application with split-thickness skin grafting
- Promotes the formation of a neovasculature and neocollagen deposition
- Tunable properties to suit a wide range of indications