EXOKĒRYX develops the Demeter EVPrep, a fully automated system that utilizes microfluidics and dielectrophoresis for the isolation of extracellular vesicles from biofluids, ensuring high recovery and purity. This technology addresses the challenge of achieving reproducible and sensitive analysis of EVs, enabling researchers to identify diseases at earlier stages.
Funding
$13.8M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Extracellular vesicle (EV) research is hindered by the difficulty of isolating EVs with both high recovery and purity, which is crucial for reproducible and sensitive downstream analysis. Current EV isolation methods often require researchers to compromise between these two critical factors, limiting the ability to accurately identify and study EVs for disease detection and monitoring.
Solution
EXOKĒRYX offers the Demeter EVPrep, a fully automated system that utilizes microfluidics and dielectrophoresis to isolate EVs from biofluids. This system overcomes the trade-off between recovery and purity by selectively isolating EVs based on their unique dipole moment, while simultaneously washing away other sample components. Researchers simply load their samples into biochip cartridges, insert them into the instrument, and initiate the automated run. The resulting isolated and concentrated EVs are then ready for downstream analyses, enabling more reliable and sensitive EV research.
Target Audience
The primary target audience includes researchers in academia and industry who are focused on extracellular vesicle research, biomarker discovery, and diagnostics development.
Features
- Fully automated EV isolation process, minimizing manual intervention and variability
- Microfluidics-based system for precise control and efficient sample processing
- Dielectrophoresis technology to selectively isolate EVs based on their unique electrical properties
- Biochip cartridges for easy sample loading and handling
- High recovery and purity of isolated EVs, ensuring reliable downstream analysis
- Compatibility with various biofluids