Exo Therapeutics

About Exo Therapeutics

Exo Therapeutics utilizes its ExoSight™ platform to identify and develop small molecule inhibitors targeting exosites on enzymes involved in oncology and inflammation. This approach aims to enhance the modulation of enzyme activity, addressing the challenge of drugging previously inaccessible targets.

```xml <problem> Many enzymes implicated in oncology and inflammation are difficult to target with traditional active-site inhibitors, limiting therapeutic options. These enzymes often possess exosites, allosteric binding pockets distinct from the active site, which can modulate enzyme activity but are challenging to identify and drug. </problem> <solution> Exo Therapeutics leverages its ExoSight™ platform to discover and develop small molecule inhibitors that target exosites on enzymes relevant to oncology and inflammation. By focusing on these exosites, Exo Therapeutics aims to achieve more precise and potent modulation of enzyme activity compared to conventional active-site targeting. This approach expands the druggable target space, potentially unlocking new therapeutic interventions for diseases where traditional methods have proven insufficient. The ExoSight™ platform provides a comprehensive approach to identify and characterize exosites, enabling the design of selective inhibitors. </solution> <features> - ExoSight™ platform for exosite identification and characterization - Development of small molecule inhibitors targeting enzyme exosites - Focus on oncology and inflammation pathways - Precise and potent modulation of enzyme activity - Potential to drug previously intractable targets </features> <target_audience> The primary target audience includes patients with cancer and inflammatory diseases, as well as pharmaceutical companies seeking novel drug targets and therapeutic strategies. </target_audience> ```

What does Exo Therapeutics do?

Exo Therapeutics utilizes its ExoSight™ platform to identify and develop small molecule inhibitors targeting exosites on enzymes involved in oncology and inflammation. This approach aims to enhance the modulation of enzyme activity, addressing the challenge of drugging previously inaccessible targets.

Where is Exo Therapeutics located?

Exo Therapeutics is based in Cambridge, United Kingdom.

When was Exo Therapeutics founded?

Exo Therapeutics was founded in 2018.

How much funding has Exo Therapeutics raised?

Exo Therapeutics has raised 102820000.

Location
Cambridge, United Kingdom
Founded
2018
Funding
102820000
Employees
19 employees

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Exo Therapeutics

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Executive Summary

Exo Therapeutics utilizes its ExoSight™ platform to identify and develop small molecule inhibitors targeting exosites on enzymes involved in oncology and inflammation. This approach aims to enhance the modulation of enzyme activity, addressing the challenge of drugging previously inaccessible targets.

exo-therapeutics.com3K+
Founded 2018Cambridge, United Kingdom

Funding

$

Estimated Funding

$100M+

Team (15+)

No team information available.

Company Description

Problem

Many enzymes implicated in oncology and inflammation are difficult to target with traditional active-site inhibitors, limiting therapeutic options. These enzymes often possess exosites, allosteric binding pockets distinct from the active site, which can modulate enzyme activity but are challenging to identify and drug.

Solution

Exo Therapeutics leverages its ExoSight™ platform to discover and develop small molecule inhibitors that target exosites on enzymes relevant to oncology and inflammation. By focusing on these exosites, Exo Therapeutics aims to achieve more precise and potent modulation of enzyme activity compared to conventional active-site targeting. This approach expands the druggable target space, potentially unlocking new therapeutic interventions for diseases where traditional methods have proven insufficient. The ExoSight™ platform provides a comprehensive approach to identify and characterize exosites, enabling the design of selective inhibitors.

Features

ExoSight™ platform for exosite identification and characterization

Development of small molecule inhibitors targeting enzyme exosites

Focus on oncology and inflammation pathways

Precise and potent modulation of enzyme activity

Potential to drug previously intractable targets

Target Audience

The primary target audience includes patients with cancer and inflammatory diseases, as well as pharmaceutical companies seeking novel drug targets and therapeutic strategies.

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