The startup develops a spectroscopy tool that analyzes protein conformations and biomolecular interactions under physiologically relevant conditions, providing real-time data analysis and visualization through cloud connectivity. This technology enables researchers in biophysics, life sciences, drug discovery, and medical diagnostics to gain insights into protein behavior, facilitating more effective scientific discoveries.
Funding
$5.1M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional methods for analyzing protein conformations and biomolecular interactions often require specialized facilities, complex experimental setups, and are limited to static snapshots, hindering a comprehensive understanding of biomolecular behavior under physiologically relevant conditions. These limitations impede advancements in biophysics, drug discovery, and diagnostics.
Solution
Exciting Instruments offers the EI-FLEX, a benchtop single-molecule fluorescence spectrometer that simplifies the study of protein conformations and biomolecular interactions in solution. The EI-FLEX enables researchers to perform single-molecule FRET (smFRET) and Fluorescence Correlation Spectroscopy (FCS) experiments without the need for optical tables or dark rooms. Its intuitive software provides real-time data analysis and publication-ready plots, making single-molecule biophysics accessible to both new and experienced users. The instrument facilitates the exploration of protein conformational landscapes, verification of protein structures, and investigation of binding and diffusion processes, all under biologically relevant conditions. By democratizing single-molecule biophysics, Exciting Instruments aims to accelerate discoveries in life science research, drug development, and diagnostics.
Target Audience
The primary target audience includes researchers in biophysics, life sciences, drug discovery, and medical diagnostics who seek to gain deeper insights into protein behavior and biomolecular interactions.
Features
- Compact, benchtop instrument suitable for any lab environment, including glovebox integration
- Two-color, single-molecule fluorescence detection in solution
- Real-time data analysis and visualization with publication-quality figures
- Intuitive software for smFRET and FCS experiments, accessible to both novice and expert users
- Capability for two-color alternating laser excitation (ALEX) and continuous wave laser excitation
- Modular system design that can be expanded to meet evolving research needs
- Optional environmental temperature control (25-60 °C)
- Compatible with protein and nucleic acid interaction studies, conformational dynamics analysis, and drug development applications
- Cloud connectivity for comprehensive data archiving and remote access