EvoWorks offers a modular, single‑use cell‑culture platform that scales from 250 mL shake‑flask volumes to 30 L bioreactor capacity on the same hardware. The system provides real‑time pH, dissolved oxygen, and CO₂ monitoring with automated data logging, eliminating cleaning validation and reducing scale‑up risk for preclinical labs, CDMOs, and CROs.
Funding
Funding not disclosed
Founders
Product
Problem
Preclinical and early‑stage biologics teams often face a gap between low‑cost shake‑flask experiments and expensive, facility‑intensive bioreactors, leading to inconsistent product quality, high contamination risk, and costly scale‑up re‑validation.
Solution
EvoWorks provides an elastically scalable cell‑culture platform that lets users grow cells in single‑use vessels ranging from 250 mL to 30 L on the same hardware. The system integrates optional real‑time pH, dissolved oxygen, and dissolved CO₂ sensors with automated data logging, delivering controlled, reproducible runs without the capital outlay of traditional bioreactors. Its modular architecture allows labs to start with a single EvoNode vessel and expand to an array of up to 18 nodes, preserving process conditions and product consistency across scales. The single‑use design eliminates cleaning validation and cross‑contamination, while the platform fits standard incubators and biosafety cabinets, requiring minimal training and no specialized facilities. This enables preclinical labs, CDMOs, and CROs to accelerate development timelines and reduce scale‑up risk.
Target Audience
Primary customers are preclinical research teams, contract development and manufacturing organizations, and contract research organizations that need affordable, reproducible scale‑up from shake‑flask to bioreactor volumes.
Features
- Single‑use EvoNode vessels (250–550 mL) with aseptic sampling ports and gas‑exchange membrane
- Modular EvoNode Mono for parallel screening of up to 12 vessels with optional per‑vessel sensing
- EvoNode Array configuration linking up to 18 vessels for seamless scale‑up to 30 L+ with single‑line fill/drain
- Real‑time monitoring of pH (±0.02), DO (±2 %), and DCO₂ via optical probes and automatic data logging
- Compatibility with existing shaking incubators and biosafety cabinets; no clean‑room requirements
- Rapid deployment: operational within 1–2 weeks for mono and 2–4 weeks for array configurations
- Automated fill, feed delivery, and sampling to reduce manual handling and contamination risk