EsoCap Biotech offers a microfluidic platform that isolates intact capillary networks from tissue samples while preserving their native 3D geometry. The system combines gentle enzymatic digestion with a proprietary capture matrix, enabling high‑resolution imaging and automated morphometric analysis for research, drug screening, and biomarker development.
Funding
$27.6M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Researchers and clinicians lack a standardized, high‑throughput method for capturing and analyzing the three‑dimensional architecture of capillary networks in tissue samples, which hampers quantitative studies of microvascular health and disease.
Solution
EsoCap Biotech develops a microfluidic platform that isolates intact capillary structures from biological tissues and preserves their native geometry for downstream imaging and analysis. The system integrates gentle enzymatic digestion with a proprietary capillary capture matrix, enabling consistent extraction of microvascular networks without distortion. Extracted capillaries can be stained, imaged with confocal or light‑sheet microscopy, and processed using automated image‑analysis pipelines that quantify parameters such as vessel diameter, branching density, and tortuosity. By providing a reproducible workflow from tissue to quantitative data, the platform supports basic research, drug screening, and diagnostic biomarker development.
Target Audience
Primary customers are academic and industry laboratories conducting microvascular research, pharmaceutical companies performing preclinical drug efficacy studies, and diagnostic firms developing vascular biomarkers.
Features
- Microfluidic cartridge with built‑in capillary capture matrix for gentle, distortion‑free isolation
- Compatible with a range of tissue types (e.g., skin, muscle, organ biopsies)
- Integrated staining protocol and optical clearing steps for high‑resolution 3D imaging
- Automated software suite for vessel segmentation, morphometric analysis, and statistical reporting
- Scalable workflow suitable for single‑sample studies or high‑throughput screening