Epigenica develops the EpiFinder™ platform, a multiplexed ChIP-seq technology that enables high-throughput epigenetic profiling of DNA methylation and histone modifications from minimal input material. This platform allows researchers to generate up to 192 quantitative genome-wide profiles simultaneously, significantly enhancing the efficiency and scalability of epigenetic studies.
Funding
$550K raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Current epigenomics technologies are limited in their ability to simultaneously profile multiple epigenetic marks and samples, resulting in low throughput and high costs. Researchers are often forced to screen for either DNA methylation or histone post-translational modifications (HPTMs) separately, requiring considerable input material and making quantitative comparisons across studies difficult.
Solution
Epigenica's EpiFinder™ platform is a multiplexed ChIP-seq technology that enables high-throughput analysis of epigenetic marks, allowing scientists to explore epigenetic biomarkers with increased speed, scalability, and affordability. Powered by the patented hmqChIP-seq technology, the EpiFinder™ platform overcomes barriers to epigenetics research by combining DNA methylation and HPTM analysis in a streamlined workflow, using low amounts of input material, and generating quantitative epigenomic maps. The EpiFinder™ Genome kit, the flagship product, allows researchers to simultaneously target up to 8 epigenetic markers in up to 24 samples, generating 192 quantitative genome-wide profiles. A customized analysis pipeline enables an automated workflow from FASTQ to demultiplexed and quantitative data.
Target Audience
The primary users are researchers in biomedical research, drug discovery and development, and precision medicine who require comprehensive, high-throughput epigenetic profiling.
Features
- High-throughput multiplexed ChIP-seq for simultaneous analysis of multiple epigenetic marks
- Patented hmqChIP-seq technology for streamlined workflow and quantitative results
- LACODE adaptor design and barcoding technology for increased throughput
- EpiFinder™ Genome kit enables targeting up to 8 epigenetic markers in up to 24 samples
- Generates up to 192 quantitative genome-wide profiles from a single experiment
- Compatible with cultured and primary cells, as well as tissue samples
- Requires low amounts of input material (1M cells/sample for profiling up to 8 hPTMs)
- Validated antibodies and optimized protocols for various starting materials
- Customized analysis pipeline for automated data processing from FASTQ to quantitative results