EpiBiologics

About EpiBiologics

EpiBiologics develops bispecific antibodies using its EpiTAC platform to selectively degrade disease-causing extracellular proteins, targeting the 40% of the proteome that intracellular methods overlook. This approach aims to enhance therapeutic efficacy for cancer and autoimmune disorders while minimizing damage to healthy tissues.

```xml <problem> Existing intracellular protein degradation methods are unable to target the 40% of the proteome consisting of extracellular proteins, limiting therapeutic options for diseases caused by these proteins. Current treatments may also lack tissue selectivity, leading to off-target effects and damage to healthy tissues. </problem> <solution> EpiBiologics is developing bispecific antibodies using its EpiTAC platform to selectively degrade disease-causing extracellular proteins. The EpiTAC platform utilizes a novel atlas of over 270 degradation-inducing protein receptors expressed on the surface of distinct tissue and cell types to create tissue-selective therapies against membrane and extracellular proteins. By directing protein degradation to specific tissues, EpiBiologics aims to enhance therapeutic efficacy while minimizing damage to healthy tissues. This approach offers a new therapeutic modality that removes the entire disease-causing protein and associated scaffolding to drive deep and long-lasting therapeutic responses. </solution> <features> - EpiTAC platform leverages a novel atlas of 270+ degradation-inducing protein receptors. - Bispecific antibodies designed for selective degradation of extracellular proteins. - Tissue-selective therapies target membrane and extracellular proteins. - Aims to degrade the entire disease-causing protein and associated scaffolding. </features> <target_audience> The primary target audience includes patients with cancer, autoimmune disorders, and other serious diseases treatable through targeted extracellular protein degradation. </target_audience> ```

What does EpiBiologics do?

EpiBiologics develops bispecific antibodies using its EpiTAC platform to selectively degrade disease-causing extracellular proteins, targeting the 40% of the proteome that intracellular methods overlook. This approach aims to enhance therapeutic efficacy for cancer and autoimmune disorders while minimizing damage to healthy tissues.

Where is EpiBiologics located?

EpiBiologics is based in San Mateo, Philippines.

When was EpiBiologics founded?

EpiBiologics was founded in 2022.

How much funding has EpiBiologics raised?

EpiBiologics has raised 73000000.

Who founded EpiBiologics?

EpiBiologics was founded by Jim Wells.

  • Jim Wells - Founder
Location
San Mateo, Philippines
Founded
2022
Funding
73000000
Employees
38 employees
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EpiBiologics

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Executive Summary

EpiBiologics develops bispecific antibodies using its EpiTAC platform to selectively degrade disease-causing extracellular proteins, targeting the 40% of the proteome that intracellular methods overlook. This approach aims to enhance therapeutic efficacy for cancer and autoimmune disorders while minimizing damage to healthy tissues.

epibiologics.com3K+
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Crunchbase
Founded 2022San Mateo, Philippines

Funding

$

Estimated Funding

$73M+

Team (30+)

Jim Wells

Founder

Company Description

Problem

Existing intracellular protein degradation methods are unable to target the 40% of the proteome consisting of extracellular proteins, limiting therapeutic options for diseases caused by these proteins. Current treatments may also lack tissue selectivity, leading to off-target effects and damage to healthy tissues.

Solution

EpiBiologics is developing bispecific antibodies using its EpiTAC platform to selectively degrade disease-causing extracellular proteins. The EpiTAC platform utilizes a novel atlas of over 270 degradation-inducing protein receptors expressed on the surface of distinct tissue and cell types to create tissue-selective therapies against membrane and extracellular proteins. By directing protein degradation to specific tissues, EpiBiologics aims to enhance therapeutic efficacy while minimizing damage to healthy tissues. This approach offers a new therapeutic modality that removes the entire disease-causing protein and associated scaffolding to drive deep and long-lasting therapeutic responses.

Features

EpiTAC platform leverages a novel atlas of 270+ degradation-inducing protein receptors.

Bispecific antibodies designed for selective degradation of extracellular proteins.

Tissue-selective therapies target membrane and extracellular proteins.

Aims to degrade the entire disease-causing protein and associated scaffolding.

Target Audience

The primary target audience includes patients with cancer, autoimmune disorders, and other serious diseases treatable through targeted extracellular protein degradation.