Envue Technologies offers a label-free optical biosensing method for the characterization of single nanoparticles, enabling precise analysis of molecular weight, interactions, and conformations. This technology addresses the challenge of studying freely moving nano-objects, providing researchers with a sensitive and easy-to-use tool for in-depth molecular analysis.
Funding
$100K raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Characterizing freely moving nano-objects, such as biomolecules and nanoparticles, is challenging due to their small size and rapid diffusion, hindering in-depth analysis of their molecular weight, interactions, and conformations. Traditional methods often require labeling or immobilization, which can alter the native state and behavior of these nano-objects, leading to inaccurate results.
Solution
Envue Technologies offers Nanofluidic Scattering Microscopy (NSM), a label-free optical microscopy technique that enables high-resolution imaging and characterization of freely moving biomolecules and biological nanoparticles. NSM utilizes nanofluidic channels as tiny optical sensors, detecting the interference effect between the scattering from the empty nanochannels and the nanochannels containing a nano-object. This method allows for real-time monitoring of single nanoparticles in solution, providing accurate measurements of their molecular weight, hydrodynamic radius, and concentration without the need for labeling or surface binding. The technology addresses the limitations of existing methods by enabling the detection of low-scattering biomolecules, even in complex mixtures, while they diffuse naturally in solution. NSM facilitates the assessment of sample purity, formulation quality, and the monitoring of nanoparticle and protein stability.
Target Audience
The primary target audience includes researchers and companies in the fields of pharmaceuticals, biotechnology, and nanomedicine who require precise characterization of nanoparticles and biomolecules for drug development, vaccine research, and bioanalysis.
Features
- Label-free characterization of single nanoparticles and biomolecules in solution
- Nanofluidic Scattering Microscopy (NSM) technology for high-resolution imaging
- Real-time monitoring of molecular weight, hydrodynamic radius, and concentration
- Detection of low-scattering biomolecules in complex mixtures
- Nanofluidic channels acting as tiny optical sensors
- No immobilization or labeling required, preserving the native state of the nano-objects
- Enables assessment of sample purity, formulation quality, and population heterogeneity