Envivo Bio has developed the CapScan® device, a non-invasive, ingestible tool that collects microbiome samples from multiple regions of the gastrointestinal tract, enabling precise analysis of gut microbiota and metabolites. This technology addresses the limitations of traditional sampling methods, providing critical insights into gut health and its impact on metabolism, immunology, and disease.
Funding
Funding not disclosed
Founders
Product
Problem
Traditional methods of sampling the gut microbiome, such as stool collection or endoscopic biopsies, provide limited insight into the regional variations and dynamic processes occurring within the gastrointestinal tract. These methods fail to capture the complexity of the gut environment, hindering the understanding of host-microbiome interactions and their impact on health and disease.
Solution
Envivo Bio has developed CapScan, an ingestible device that enables multi-region sampling of the gut microbiome and metabolome. The device is designed with a pH-sensitive coating that dissolves at specific locations within the intestinal tract, allowing for targeted sample collection. Once the coating dissolves, the device opens and collects luminal content, which can then be analyzed to measure microbiota composition, metabolites, and other biomarkers. This approach provides a more comprehensive understanding of the gut environment compared to traditional sampling methods, enabling researchers to study regional differences and dynamic changes in the gut.
Target Audience
Envivo Bio's primary customers are biotechnology firms, pharmaceutical companies, and academic scientists seeking to accelerate their clinical research and drug discovery and development programs related to the gut microbiome.
Features
- Non-invasive, ingestible device for sampling the gut microbiome and metabolome
- pH-targeted enteric coating for controlled sample collection at specific intestinal regions
- Multi-omics analysis to measure microbial, viral, proteomic, and bile acid profiles
- Identification of novel metabolites and microbial species not found in stool samples
- Spatiotemporal profiling of the gut metabolome during routine daily digestion