Enduro Genetics provides Enduro Sense, a genetic plugin that enhances the performance of production strains by linking high product yield to cell growth, thereby maintaining a stable population of high-producing variants during fermentation. This technology addresses the issue of declining production efficiency in large-scale bioproduction by ensuring consistent high yields and titer across various organisms and processes.
Funding
$3.6M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
In large-scale bioproduction, production strains often suffer from declining efficiency due to the emergence of faster-growing, lower-producing cell variants during fermentation. This instability compromises the overall yield and titer of the desired bioproduct over extended production runs.
Solution
Enduro Genetics offers Enduro Sense, a genetic plugin that stabilizes production strain performance by linking high product yield to cell growth. This technology ensures that high-producing cell variants maintain a stable population during fermentation, preventing the enrichment of lower-producing cells. By making cells "addicted" to high production, Enduro Sense sustains elevated production levels throughout the fermentation process, resulting in higher overall yields and titers. The plugin can be seamlessly integrated into existing commercial strains or used from the initial design phase without requiring changes to the cultivation medium.
Target Audience
Enduro Genetics serves companies involved in large-scale bioproduction across various industries, including those producing food ingredients, pharmaceuticals, and industrial enzymes.
Features
- Genetic plugin that couples high production levels to cell growth, stabilizing production strain performance.
- Increases the proportion of high-producing cell variants within the population.
- Maintains elevated production levels throughout the fermentation process.
- Seamless integration into existing commercial strains without cultivation medium changes.
- Compatible with various bioproduct types.
- Enables production of complex or cellular-inhibiting products by overcoming strain instability.
- Accelerates strain development through selection of stable, high-producing strains.
- Free of antibiotic resistance genes for compliant and safe handling.