Enantios offers Raman optical activity (ROA) measurement instruments and a measurement‑as‑a‑service platform for analyzing chiral small molecules and biologics. Their technology eliminates the need for chiral‑HPLC, crystallization, or purified reference standards, enabling rapid absolute configuration and enantiomeric excess determination. This supports pharmaceutical R&D and manufacturing by reducing development time and cost while fitting into glove‑box environments.
Funding
$2M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
PGFounders
Product
Problem
Characterizing the structure of complex chiral molecules and biologics is crucial for understanding their interactions within biological systems, yet traditional methods like chiral-HPLC and crystallization can be time-consuming, require purified reference standards, and may not be suitable for all molecules. This can slow down drug discovery and increase manufacturing costs in the pharmaceutical industry.
Solution
Enantios offers a benchtop Raman optical activity (ROA) instrument and measurement services that provide detailed analysis of chirality, molecular structure, and solvent effects. The instrument utilizes a patented optical design to simplify ROA measurements, eliminating the need for expert users and complex laser alignment. This technology enables researchers to determine absolute configuration, isomeric/enantiomeric excess, and structural motifs of biologics directly in solution, without requiring crystallization or chiral-HPLC. Enantios' solutions accelerate drug discovery and development by providing rapid, accurate structural information for small molecules and biologics.
Target Audience
The primary target audience includes researchers and scientists in the pharmaceutical industry, academia, and research facilities who need to characterize chiral molecules and biologics.
Features
- Measures Raman optical activity (ROA) to differentiate between enantiomers and determine enantiomeric excess.
- Determines absolute configuration of chiral small molecules without crystallization or HPLC.
- Analyzes secondary and tertiary structural motifs of biologics in solution.
- Provides structural stability and degradation testing for proteins and antibodies.
- Features a user-friendly software interface for simplified operation.
- Offers low-volume and low-cost measurement vials.
- Full redesign of the optics to minimize artifacts and misalignment