Element Biosciences offers the AVAVI family of benchtop sequencers that perform spatial, single‑cell co‑detection of RNA, protein, and cell morphology using Direct‑In‑Sample Sequencing and Avidite Base Chemistry. The platform eliminates library‑preparation steps, delivers up to 50 % more data per run with high‑accuracy reads, and streams results to the ElemBio Cloud for automated analysis within 24 hours.
Funding
$277M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
WMFounders
Product
Problem
Researchers need high‑resolution, spatially resolved multiomics data but current sequencing workflows require costly instruments, extensive library preparation, and separate assays for RNA, protein, and morphology, limiting throughput and affordability.
Solution
Element Biosciences delivers the AVAVI family of integrated sequencing platforms that combine proprietary Avidite Base Chemistry (ABC) with Direct‑In‑Sample Sequencing (DISS). The system performs spatial, single‑cell co‑detection of RNA, protein, and cell morphology on a single benchtop instrument, eliminating library‑prep steps and reducing turnaround to 24 hours. By leveraging ABC chemistry, the platform generates high‑accuracy reads with up to 50 % more data per run compared to competing sequencers, while maintaining a lower cost per gigabase. Results are streamed to ElemBio Cloud for automated analysis, storage, and optional AI‑driven interpretation. The end‑to‑end solution enables labs to profile complex biological systems rapidly and at scale without fragmented workflows.
Target Audience
Primary customers are academic research institutions, biotech and pharmaceutical R&D labs, and agricultural genomics programs that require high‑throughput spatial multiomics and single‑cell sequencing capabilities.
Features
- AVITI24 benchtop sequencer with 20 cm² imaging area for subcellular spatial resolution
- Direct‑In‑Sample Sequencing (DISS) workflow that removes all library‑preparation steps
- ABC™ (Avidite Base Chemistry) delivering high‑accuracy reads and up to 50 % increased data yield per run
- Simultaneous detection of RNA transcripts, protein epitopes, and cell morphology in a single assay (5D multiomics)
- 24‑hour run time for full spatial‑single‑cell datasets
- Integrated cloud platform (ElemBio Cloud) for data upload, automated QC, and scalable analytics
- Compatible reagent kits (Cloudbreak, Trinity, Teton CytoProfiling) and library adapters (Elevate, Adept) for flexible assay design
- Compact design suitable for labs of any size, with optional service contracts and certified service‑provider network