Elegen utilizes proprietary cell-free DNA synthesis technology to produce long, complex, linear DNA up to 7 kb with 99.999% accuracy, eliminating the need for cloning. This rapid synthesis, delivered in 6 to 8 business days, addresses the critical bottleneck in DNA supply for synthetic biology applications, significantly reducing project timelines and costs.
Funding
$56.6M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Synthetic biology workflows are often bottlenecked by the time and cost associated with traditional DNA synthesis methods, particularly when producing long, complex sequences. Cloning-based approaches are labor-intensive, error-prone, and can significantly extend project timelines. Researchers require faster access to high-quality DNA to accelerate their research and development cycles.
Solution
Elegen provides rapid, high-accuracy, cell-free DNA synthesis, delivering linear DNA constructs up to 7 kb in length within 6-8 business days. Their ENFINIA DNA eliminates the need for cloning, streamlining synthetic biology workflows and reducing project timelines by weeks or months. The NGS-verified DNA, boasting an error rate as low as 1:70,000 bp, can be directly integrated into downstream applications, such as mRNA vaccine development, cell and gene therapy, and biomanufacturing, without the need for traditional cloning or master cell banks. Elegen's technology enables researchers to iterate faster, explore a broader sequence space, and accelerate the development of novel biological solutions.
Target Audience
Elegen's primary customers include synthetic biologists, researchers in cell and gene therapy, mRNA vaccine development, agricultural biology, and biomanufacturing, as well as other scientists who require rapid access to high-quality, complex DNA sequences.
Features
- Cell-free DNA synthesis technology for rapid production of long, complex DNA
- NGS verification to ensure high accuracy (error rates as low as 1:70,000 bp)
- Linear DNA constructs up to 7 kb in length
- Turnaround time of 6-8 business days for standard sequences, and as fast as 10 days for high-complexity sequences
- Ability to synthesize sequences with high complexity, including long repeats, STRs, GC-rich regions, and homopolymers
- Customizable synthesis yields (1-3 µg, 5-15 µg, or 20-60 µg)
- Delivered as dried-down, double-stranded DNA in a 96-well plate with defined adapter sequences
- Streamlined workflow, eliminating the need for cloning and master cell banks in many applications