Eclipse Bioinnovations provides RNA profiling and analytics solutions, including the eMERGE platform, to enhance the development of mRNA, saRNA, and circRNA therapies. Their technology addresses challenges in potency, stability, and safety, enabling researchers and developers to advance RNA-based medicines with confidence.
Funding
$19M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
AVIFounders
Product
Problem
Developing effective mRNA, saRNA, and circRNA therapies faces challenges related to potency, stability, safety, and off-target effects, hindering the advancement of RNA-based medicines. Existing methods often lack comprehensive characterization and precision optimization, leading to uncertainty in therapeutic development.
Solution
Eclipse Bioinnovations offers RNA profiling and analytics solutions, including the eMERGE platform, designed to address critical challenges in RNA-based medicine development. Their technology portfolio provides insights into potency, stability, and safety, enabling researchers to advance RNA therapies with greater confidence. By integrating proprietary technologies and bioinformatics workflows, Eclipsebio delivers actionable insights into major dimensions of RNA and therapeutic biology. The eMERGE platform offers a comprehensive approach to characterizing and optimizing RNA therapeutics, facilitating the transition to clinical trials.
Target Audience
The primary audience includes researchers and developers involved in mRNA, saRNA, circRNA, RNAi, and ASO therapeutics, as well as those focused on target discovery and validation for small molecule drugs.
Features
- **eMERGE Platform:** Integrates assays and bioinformatics workflows for comprehensive RNA characterization.
- **End-Seq:** Maps unique regulatory regions within RNA sequences.
- **eRibo Pro:** Measures transcription and translation activity.
- **eSENSE dsRNA:** Quantifies and reduces double-stranded RNA (dsRNA) contamination.
- **eSENSE m6A:** Maps regions of RNA methylation.
- **eSHAPE:** Directly determines RNA structure.
- **m6A-eCLIP & miR-eCLIP & RBP-eCLIP:** Identifies RNA-protein interactions and miRNA/siRNA binding sites.
- **eVERSE platform:** Provides reproducible datasets for AI model training in drug discovery.
- **Bioinformatics:** Offers integrative analysis solutions for multiomic data.