DEL Source provides DNA‑Encoded Library (DEL) solutions that combine synthetic chemistry, high‑throughput screening, and AI/ML analytics to speed up small‑molecule drug discovery. Customers can purchase off‑the‑shelf DELs—over a dozen libraries with full enumeration and structural data—or request custom libraries such as covalent, PROTAC, and molecular glue collections, along with hit‑identification screening services to generate large‑scale DEL datasets for their programs.
Funding
Funding not disclosed
Founders
Product
Problem
Drug discovery teams often face long timelines and high costs when generating and screening small‑molecule libraries, especially for specialized modalities such as covalent inhibitors, PROTACs, or molecular glues. Limited access to diverse, well‑characterized DNA‑Encoded Libraries (DELs) and integrated data analysis hampers rapid hit identification and lead optimization.
Solution
DEL Source offers a suite of DNA‑Encoded Library products and services that combine modern synthetic chemistry with AI/ML‑enhanced screening to streamline small‑molecule discovery. Their catalog includes off‑the‑shelf DELs, as well as custom‑synthesized libraries tailored for covalent, PROTAC, and molecular glue chemotypes. The company conducts high‑throughput DEL screening, hit identification, and subsequent hit re‑synthesis with activity confirmation, delivering validated chemical leads. Large‑scale DEL datasets are generated and made available to support data‑driven decision making. Expert support throughout library design, synthesis, and screening helps accelerate lead generation while reducing cost and cycle time.
Target Audience
Primary customers are pharmaceutical and biotech R&D teams, as well as academic drug discovery groups, seeking rapid generation of high‑quality small‑molecule hits for diverse therapeutic targets.
Features
- Portfolio of more than a dozen fully enumerated off‑the‑shelf DELs with complete structural annotation
- Custom library design and one‑step synthesis for covalent, PROTAC, and molecular glue modalities
- Integrated AI/ML pipelines for hit identification, data analysis, and SAR exploration
- End‑to‑end service flow: library synthesis, high‑throughput screening, hit re‑synthesis, and activity confirmation
- Large‑scale DEL datasets provided to customers for downstream computational modeling
- Expert support covering library strategy, chemistry, and screening workflow