CrannMed is developing resorbable microspheres and a custom delivery catheter for Genicular Artery Embolization to treat knee osteoarthritis by blocking small blood vessels, thereby reducing inflammation and pain. This approach addresses the chronic swelling and degradation cycle of the disease, offering a potential alternative to more invasive treatments like knee replacement surgery.
Funding
$3M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Knee osteoarthritis (KOA) affects millions globally, causing chronic pain and disability due to joint swelling and cartilage degradation. Current treatments primarily manage pain without addressing the underlying causes, often leading to more invasive interventions like knee replacement surgery.
Solution
CrannMed is developing SakuraBead, a resorbable microsphere technology delivered via Genicular Artery Embolization (GAE) to treat knee osteoarthritis. The microspheres are designed to block small blood vessels proliferating in the soft tissue of the osteoarthritic knee, reducing inflammation and pain. By interrupting the degradation cycle of osteoarthritis, SakuraBead aims to slow or halt disease progression, offering a potential alternative to more aggressive treatments. The resorbable nature of the microspheres increases safety by reducing the risk of non-target embolization, facilitates potential re-intervention, and allows for the full restoration of vascular circulation.
Target Audience
The primary target audience includes interventional radiologists, orthopedic surgeons, and pain management specialists treating patients with knee osteoarthritis, as well as patients seeking alternatives to traditional pain management and invasive surgical procedures.
Features
- Precisely calibrated microspheres made from organic, resorbable materials.
- Optimized for Genicular Artery Embolization (GAE) to target small vessels in the knee.
- Designed to reduce inflammation and pain associated with knee osteoarthritis.
- Aims to disrupt the osteoarthritic degradation cycle to slow or halt disease progression.
- Resorbable material facilitates re-intervention and restores vascular circulation.
- Custom delivery catheter for precise and targeted microsphere placement.