Codomax provides the Epi-MAX Platform, an integrated suite of omics and analytics tools designed for cell and gene engineering. This platform leverages novel insights into cellular stress response and tRNA reprogramming to optimize high-yielding protein production. The technology supports scalable protein manufacturing, strain engineering, and mRNA therapeutics development.
Funding
Funding not disclosed
Founders
Product
Problem
The biomanufacturing industry faces challenges in efficiently producing complex proteins at high yields while maintaining their native properties, often due to limitations in cellular translation mechanisms and stress responses during production. Traditional methods struggle with low protein output and extended processing times, hindering the cost-effective production of biologics and alternative food proteins.
Solution
Codomax offers the Epi-MAX platform, an integrated suite of omics-based tools that reprograms cells to enhance the biomanufacturing of difficult-to-express proteins. By analyzing cellular stress responses and translational machinery, Epi-MAX re-engineers cells and their genes to maximize protein yields under biomanufacturing conditions. The platform leverages tRNA-centric engineering, optimizing a cell's pool of tRNAs and their modifications to improve protein production. This approach harmonizes a cell's biology with its environment, resulting in increased protein yields and retention of native properties. Codomax's technology addresses bottlenecks in protein production, enabling the cost-effective and scalable manufacturing of therapeutics and alternative foods.
Target Audience
Codomax serves the biomanufacturing industry, including companies producing biologics, alternative food proteins, and gene therapies, as well as researchers in strain engineering and synthetic biology.
Features
- Systems-level, omics-based measurements of cellular stress responses
- Computational analysis of cellular translational machinery
- tRNA-centric engineering to optimize protein production
- Re-engineering of cells and genes to maximize protein yields
- Compatibility with any cell type and production conditions
- Plug-and-play integration with complementary technologies
- Data-driven software guided by experimental measurements
- Harmonization of cell biology to function optimally under environmental conditions and stressors